Fang Z - Search Results

1

Synthesis and biological characterization of 1,4,5,6-tetrahydropyrimidine and 2-amino-3,4,5,6-tetrahydropyridine derivatives as selective m1 agonists.

Messer WS Jr, Abuh YF, Liu Y, Periyasamy S, Ngur DO, Edgar MA, El-Assadi AA, Sbeih S, Dunbar PG, Roknich S, Rho T, Fang Z, Ojo B, Zhang H, Huzl JJ 3rd, Nagy PI. Messer WS Jr, et al. Among authors: fang z. J Med Chem. 1997 Apr 11;40(8):1230-46. doi: 10.1021/jm960467d. J Med Chem. 1997. PMID: 9111297

2

Design, synthesis, and neurochemical evaluation of 5-(3-alkyl-1,2,4- oxadiazol-5-yl)-1,4,5,6-tetrahydropyrimidines as M1 muscarinic receptor agonists.

Dunbar PG, Durant GJ, Fang Z, Abuh YF, el-Assadi AA, Ngur DO, Periyasamy S, Hoss WP, Messer WS Jr. Dunbar PG, et al. Among authors: fang z. J Med Chem. 1993 Apr 2;36(7):842-7. doi: 10.1021/jm00059a008. J Med Chem. 1993. PMID: 8464038

3

Design, Synthesis, and Evaluation of Thiophene[3,2-d]pyrimidine Derivatives as HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Significantly Improved Drug Resistance Profiles.

Kang D, Fang Z, Li Z, Huang B, Zhang H, Lu X, Xu H, Zhou Z, Ding X, Daelemans D, De Clercq E, Pannecouque C, Zhan P, Liu X. Kang D, et al. Among authors: fang z. J Med Chem. 2016 Sep 8;59(17):7991-8007. doi: 10.1021/acs.jmedchem.6b00738. Epub 2016 Aug 26. J Med Chem. 2016. PMID: 27541578

4

Novel 1,2,3-thiadiazole derivatives as HIV-1 NNRTIs with improved potency: Synthesis and preliminary SAR studies.

Zhan P, Liu X, Li Z, Fang Z, Li Z, Wang D, Pannecouque C, Clercq ED. Zhan P, et al. Among authors: fang z. Bioorg Med Chem. 2009 Aug 15;17(16):5920-7. doi: 10.1016/j.bmc.2009.07.004. Epub 2009 Jul 7. Bioorg Med Chem. 2009. PMID: 19620009

5

Synthesis and anti-HIV activity evaluation of 2-(4-(naphthalen-2-yl)-1,2,3-thiadiazol-5-ylthio)-N-acetamides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.

Zhan P, Liu X, Fang Z, Li Z, Pannecouque C, De Clercq E. Zhan P, et al. Among authors: fang z. Eur J Med Chem. 2009 Nov;44(11):4648-53. doi: 10.1016/j.ejmech.2009.06.037. Epub 2009 Jul 4. Eur J Med Chem. 2009. PMID: 19628308

6

Synthesis and biological evaluation of imidazole thioacetanilides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.

Zhan P, Liu X, Zhu J, Fang Z, Li Z, Pannecouque C, Clercq ED. Zhan P, et al. Among authors: fang z. Bioorg Med Chem. 2009 Aug 15;17(16):5775-81. doi: 10.1016/j.bmc.2009.07.028. Epub 2009 Jul 18. Bioorg Med Chem. 2009. PMID: 19643613

7

Optimization of N-Substituted Oseltamivir Derivatives as Potent Inhibitors of Group-1 and -2 Influenza A Neuraminidases, Including a Drug-Resistant Variant.

Zhang J, Poongavanam V, Kang D, Bertagnin C, Lu H, Kong X, Ju H, Lu X, Gao P, Tian Y, Jia H, Desta S, Ding X, Sun L, Fang Z, Huang B, Liang X, Jia R, Ma X, Xu W, Murugan NA, Loregian A, Huang B, Zhan P, Liu X. Zhang J, et al. Among authors: fang z. J Med Chem. 2018 Jul 26;61(14):6379-6397. doi: 10.1021/acs.jmedchem.8b00929. Epub 2018 Jul 16. J Med Chem. 2018. PMID: 29965752

8

1,2,3-Selenadiazole thioacetanilides: synthesis and anti-HIV activity evaluation.

Zhan P, Liu X, Fang Z, Pannecouque C, De Clercq E. Zhan P, et al. Among authors: fang z. Bioorg Med Chem. 2009 Sep 1;17(17):6374-9. doi: 10.1016/j.bmc.2009.07.027. Epub 2009 Jul 18. Bioorg Med Chem. 2009. PMID: 19647440

9

Structure-Based Optimization of Thiophene[3,2-d]pyrimidine Derivatives as Potent HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Improved Potency against Resistance-Associated Variants.

Kang D, Fang Z, Huang B, Lu X, Zhang H, Xu H, Huo Z, Zhou Z, Yu Z, Meng Q, Wu G, Ding X, Tian Y, Daelemans D, De Clercq E, Pannecouque C, Zhan P, Liu X. Kang D, et al. Among authors: fang z. J Med Chem. 2017 May 25;60(10):4424-4443. doi: 10.1021/acs.jmedchem.7b00332. Epub 2017 May 15. J Med Chem. 2017. PMID: 28481112

10

Discovery and Characterization of Fluorine-Substituted Diarylpyrimidine Derivatives as Novel HIV-1 NNRTIs with Highly Improved Resistance Profiles and Low Activity for the hERG Ion Channel.

Kang D, Ruiz FX, Feng D, Pilch A, Zhao T, Wei F, Wang Z, Sun Y, Fang Z, De Clercq E, Pannecouque C, Arnold E, Liu X, Zhan P. Kang D, et al. Among authors: fang z. J Med Chem. 2020 Feb 13;63(3):1298-1312. doi: 10.1021/acs.jmedchem.9b01769. Epub 2020 Jan 24. J Med Chem. 2020. PMID: 31935327 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

7,255 results

Search Page