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Fumonisin toxicity and sphingolipid biosynthesis.
Merrill AH Jr, Wang E, Vales TR, Smith ER, Schroeder JJ, Menaldino DS, Alexander C, Crane HM, Xia J, Liotta DC, Meredith FI, Riley RT. Merrill AH Jr, et al. Among authors: vales tr. Adv Exp Med Biol. 1996;392:297-306. doi: 10.1007/978-1-4899-1379-1_25. Adv Exp Med Biol. 1996. PMID: 8850625 Review.
Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor.
Humpf HU, Schmelz EM, Meredith FI, Vesper H, Vales TR, Wang E, Menaldino DS, Liotta DC, Merrill AH Jr. Humpf HU, et al. Among authors: vales tr. J Biol Chem. 1998 Jul 24;273(30):19060-4. doi: 10.1074/jbc.273.30.19060. J Biol Chem. 1998. PMID: 9668088 Free article.
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