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Page 1
A novel small molecule inhibitor of hepatitis C virus entry.
Baldick CJ, Wichroski MJ, Pendri A, Walsh AW, Fang J, Mazzucco CE, Pokornowski KA, Rose RE, Eggers BJ, Hsu M, Zhai W, Zhai G, Gerritz SW, Poss MA, Meanwell NA, Cockett MI, Tenney DJ. Baldick CJ, et al. Among authors: walsh aw. PLoS Pathog. 2010 Sep 2;6(9):e1001086. doi: 10.1371/journal.ppat.1001086. PLoS Pathog. 2010. PMID: 20838466 Free PMC article.
Inhibition of hepatitis B virus polymerase by entecavir.
Langley DR, Walsh AW, Baldick CJ, Eggers BJ, Rose RE, Levine SM, Kapur AJ, Colonno RJ, Tenney DJ. Langley DR, et al. Among authors: walsh aw. J Virol. 2007 Apr;81(8):3992-4001. doi: 10.1128/JVI.02395-06. Epub 2007 Jan 31. J Virol. 2007. PMID: 17267485 Free PMC article.
Two-year assessment of entecavir resistance in Lamivudine-refractory hepatitis B virus patients reveals different clinical outcomes depending on the resistance substitutions present.
Tenney DJ, Rose RE, Baldick CJ, Levine SM, Pokornowski KA, Walsh AW, Fang J, Yu CF, Zhang S, Mazzucco CE, Eggers B, Hsu M, Plym MJ, Poundstone P, Yang J, Colonno RJ. Tenney DJ, et al. Among authors: walsh aw. Antimicrob Agents Chemother. 2007 Mar;51(3):902-11. doi: 10.1128/AAC.00833-06. Epub 2006 Dec 18. Antimicrob Agents Chemother. 2007. PMID: 17178796 Free PMC article. Clinical Trial.
Clinical emergence of entecavir-resistant hepatitis B virus requires additional substitutions in virus already resistant to Lamivudine.
Tenney DJ, Levine SM, Rose RE, Walsh AW, Weinheimer SP, Discotto L, Plym M, Pokornowski K, Yu CF, Angus P, Ayres A, Bartholomeusz A, Sievert W, Thompson G, Warner N, Locarnini S, Colonno RJ. Tenney DJ, et al. Among authors: walsh aw. Antimicrob Agents Chemother. 2004 Sep;48(9):3498-507. doi: 10.1128/AAC.48.9.3498-3507.2004. Antimicrob Agents Chemother. 2004. PMID: 15328117 Free PMC article.
4-Thiazolidinones: novel inhibitors of the bacterial enzyme MurB.
Andres CJ, Bronson JJ, D'Andrea SV, Deshpande MS, Falk PJ, Grant-Young KA, Harte WE, Ho HT, Misco PF, Robertson JG, Stock D, Sun Y, Walsh AW. Andres CJ, et al. Among authors: walsh aw. Bioorg Med Chem Lett. 2000 Apr 17;10(8):715-7. doi: 10.1016/s0960-894x(00)00073-1. Bioorg Med Chem Lett. 2000. PMID: 10782671
28 results