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Chimeric receptors indicate that phenylalanine 39 is a major contributor to insulin specificity of the insulin receptor.
Kjeldsen T, Wiberg FC, Andersen AS. Kjeldsen T, et al. Among authors: andersen as. J Biol Chem. 1994 Dec 30;269(52):32942-6. J Biol Chem. 1994. PMID: 7806523 Free article.
The exact nature of how the insulin molecule interacts with the insulin receptor is obscure although chimeric receptors have shown that the ligand specificity of the insulin receptor and the IGF-I receptor (i.e. the sequences that discriminate between insulin and insulin-like gro …
The exact nature of how the insulin molecule interacts with the insulin receptor is obscure although chimeric receptors have shown that the …
100 results