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Antitumor activity of the aurora a selective kinase inhibitor, alisertib, against preclinical models of colorectal cancer.
Pitts TM, Bradshaw-Pierce EL, Bagby SM, Hyatt SL, Selby HM, Spreafico A, Tentler JJ, McPhillips K, Klauck PJ, Capasso A, Diamond JR, Davis SL, Tan AC, Arcaroli JJ, Purkey A, Messersmith WA, Ecsedy JA, Eckhardt SG. Pitts TM, et al. Among authors: hyatt sl. Oncotarget. 2016 Aug 2;7(31):50290-50301. doi: 10.18632/oncotarget.10366. Oncotarget. 2016. PMID: 27385211 Free PMC article.
Combined inhibition of MEK and Aurora A kinase in KRAS/PIK3CA double-mutant colorectal cancer models.
Davis SL, Robertson KM, Pitts TM, Tentler JJ, Bradshaw-Pierce EL, Klauck PJ, Bagby SM, Hyatt SL, Selby HM, Spreafico A, Ecsedy JA, Arcaroli JJ, Messersmith WA, Tan AC, Eckhardt SG. Davis SL, et al. Among authors: hyatt sl. Front Pharmacol. 2015 Jun 16;6:120. doi: 10.3389/fphar.2015.00120. eCollection 2015. Front Pharmacol. 2015. PMID: 26136684 Free PMC article.
Dual pharmacological targeting of the MAP kinase and PI3K/mTOR pathway in preclinical models of colorectal cancer.
Pitts TM, Newton TP, Bradshaw-Pierce EL, Addison R, Arcaroli JJ, Klauck PJ, Bagby SM, Hyatt SL, Purkey A, Tentler JJ, Tan AC, Messersmith WA, Eckhardt SG, Leong S. Pitts TM, et al. Among authors: hyatt sl. PLoS One. 2014 Nov 17;9(11):e113037. doi: 10.1371/journal.pone.0113037. eCollection 2014. PLoS One. 2014. PMID: 25401499 Free PMC article.
Optimization of hCFTR lung expression in mice using DNA nanoparticles.
Padegimas L, Kowalczyk TH, Adams S, Gedeon CR, Oette SM, Dines K, Hyatt SL, Sesenoglu-Laird O, Tyr O, Moen RC, Cooper MJ. Padegimas L, et al. Among authors: hyatt sl. Mol Ther. 2012 Jan;20(1):63-72. doi: 10.1038/mt.2011.196. Epub 2011 Sep 27. Mol Ther. 2012. PMID: 21952168 Free PMC article.
Compacted DNA nanoparticles administered to the nasal mucosa of cystic fibrosis subjects are safe and demonstrate partial to complete cystic fibrosis transmembrane regulator reconstitution.
Konstan MW, Davis PB, Wagener JS, Hilliard KA, Stern RC, Milgram LJ, Kowalczyk TH, Hyatt SL, Fink TL, Gedeon CR, Oette SM, Payne JM, Muhammad O, Ziady AG, Moen RC, Cooper MJ. Konstan MW, et al. Among authors: hyatt sl. Hum Gene Ther. 2004 Dec;15(12):1255-69. doi: 10.1089/hum.2004.15.1255. Hum Gene Ther. 2004. PMID: 15684701 Clinical Trial.
18 results