Wahhab A - Search Results

1

Differences in backbone structure between angiotensin II agonists and type I antagonists.

Matsoukas JM, Agelis G, Wahhab A, Hondrelis J, Panagiotopoulos D, Yamdagni R, Wu Q, Mavromoustakos T, Maia HL, Ganter R, et al. Matsoukas JM, et al. Among authors: wahhab a. J Med Chem. 1995 Nov 10;38(23):4660-9. doi: 10.1021/jm00023a005. J Med Chem. 1995. PMID: 7473593

2

Imidazole based non-peptide angiotensin II receptor antagonists. Investigation of the effect of the orientation of the imidazole ring on biological activity.

Wahhab A, Smith JR, Ganter RC, Moore DM, Hondrelis J, Matsoukas J, Moore GJ. Wahhab A, et al. Arzneimittelforschung. 1993 Nov;43(11):1157-68. Arzneimittelforschung. 1993. PMID: 8292058

3

Transposition of the imidazole ring substituents of angiotensin mimetics related to Losartan.

Smith JR, Wahhab A, Moore D, Ganter RC, Moore GJ. Smith JR, et al. Among authors: wahhab a. Drug Des Discov. 1994 Nov;12(2):113-9. Drug Des Discov. 1994. PMID: 9116166

4

1,2-Diamines as inhibitors of co-activator associated arginine methyltransferase 1 (CARM1).

Therrien E, Larouche G, Manku S, Allan M, Nguyen N, Styhler S, Robert MF, Goulet AC, Besterman JM, Nguyen H, Wahhab A. Therrien E, et al. Among authors: wahhab a. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6725-32. doi: 10.1016/j.bmcl.2009.09.110. Epub 2009 Oct 2. Bioorg Med Chem Lett. 2009. PMID: 19836951

5

SAR around (l)-S-adenosyl-l-homocysteine, an inhibitor of human DNA methyltransferase (DNMT) enzymes.

Saavedra OM, Isakovic L, Llewellyn DB, Zhan L, Bernstein N, Claridge S, Raeppel F, Vaisburg A, Elowe N, Petschner AJ, Rahil J, Beaulieu N, MacLeod AR, Delorme D, Besterman JM, Wahhab A. Saavedra OM, et al. Among authors: wahhab a. Bioorg Med Chem Lett. 2009 May 15;19(10):2747-51. doi: 10.1016/j.bmcl.2009.03.113. Epub 2009 Mar 28. Bioorg Med Chem Lett. 2009. PMID: 19362833

6

Constrained (l-)-S-adenosyl-l-homocysteine (SAH) analogues as DNA methyltransferase inhibitors.

Isakovic L, Saavedra OM, Llewellyn DB, Claridge S, Zhan L, Bernstein N, Vaisburg A, Elowe N, Petschner AJ, Rahil J, Beaulieu N, Gauthier F, MacLeod AR, Delorme D, Besterman JM, Wahhab A. Isakovic L, et al. Among authors: wahhab a. Bioorg Med Chem Lett. 2009 May 15;19(10):2742-6. doi: 10.1016/j.bmcl.2009.03.132. Epub 2009 Mar 28. Bioorg Med Chem Lett. 2009. PMID: 19364644

7

Discovery of a novel and potent series of thieno[3,2-b]pyridine-based inhibitors of c-Met and VEGFR2 tyrosine kinases.

Claridge S, Raeppel F, Granger MC, Bernstein N, Saavedra O, Zhan L, Llewellyn D, Wahhab A, Deziel R, Rahil J, Beaulieu N, Nguyen H, Dupont I, Barsalou A, Beaulieu C, Chute I, Gravel S, Robert MF, Lefebvre S, Dubay M, Pascal R, Gillespie J, Jin Z, Wang J, Besterman JM, MacLeod AR, Vaisburg A. Claridge S, et al. Among authors: wahhab a. Bioorg Med Chem Lett. 2008 May 1;18(9):2793-8. doi: 10.1016/j.bmcl.2008.04.009. Epub 2008 Apr 9. Bioorg Med Chem Lett. 2008. PMID: 18434145

8

Synthesis and evaluation of lysine derived sulfamides as histone deacetylase inhibitors.

Manku S, Allan M, Nguyen N, Ajamian A, Rodrigue J, Therrien E, Wang J, Guo T, Rahil J, Petschner AJ, Nicolescu A, Lefebvre S, Li Z, Fournel M, Besterman JM, Déziel R, Wahhab A. Manku S, et al. Among authors: wahhab a. Bioorg Med Chem Lett. 2009 Apr 1;19(7):1866-70. doi: 10.1016/j.bmcl.2009.02.075. Epub 2009 Feb 23. Bioorg Med Chem Lett. 2009. PMID: 19272776

9

Discovery of bicyclic pyrazoles as class III histone deacetylase SIRT1 and SIRT2 inhibitors.

Therrien E, Larouche G, Nguyen N, Rahil J, Lemieux AM, Li Z, Fournel M, Yan TP, Landry AJ, Lefebvre S, Wang JJ, MacBeth K, Heise C, Nguyen A, Besterman JM, Déziel R, Wahhab A. Therrien E, et al. Among authors: wahhab a. Bioorg Med Chem Lett. 2015 Jun 15;25(12):2514-8. doi: 10.1016/j.bmcl.2015.04.068. Epub 2015 Apr 28. Bioorg Med Chem Lett. 2015. PMID: 25971769

10

Diphenylmethylene hydroxamic acids as selective class IIa histone deacetylase inhibitors.

Tessier P, Smil DV, Wahhab A, Leit S, Rahil J, Li Z, Déziel R, Besterman JM. Tessier P, et al. Among authors: wahhab a. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5684-8. doi: 10.1016/j.bmcl.2009.08.010. Epub 2009 Aug 7. Bioorg Med Chem Lett. 2009. PMID: 19699639

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