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PARKIN is not required to sustain OXPHOS function in adult mammalian tissues.
Filograna R, Gerlach J, Choi HN, Rigoni G, Barbaro M, Oscarson M, Lee S, Tiklova K, Ringnér M, Koolmeister C, Wibom R, Riggare S, Nennesmo I, Perlmann T, Wredenberg A, Wedell A, Motori E, Svenningsson P, Larsson NG. Filograna R, et al. Among authors: svenningsson p. NPJ Parkinsons Dis. 2024 Apr 29;10(1):93. doi: 10.1038/s41531-024-00707-0. NPJ Parkinsons Dis. 2024. PMID: 38684669 Free PMC article.
Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons.
Kadkhodaei B, Alvarsson A, Schintu N, Ramsköld D, Volakakis N, Joodmardi E, Yoshitake T, Kehr J, Decressac M, Björklund A, Sandberg R, Svenningsson P, Perlmann T. Kadkhodaei B, et al. Among authors: svenningsson p. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2360-5. doi: 10.1073/pnas.1221077110. Epub 2013 Jan 22. Proc Natl Acad Sci U S A. 2013. PMID: 23341612 Free PMC article.
Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease.
Laguna A, Schintu N, Nobre A, Alvarsson A, Volakakis N, Jacobsen JK, Gómez-Galán M, Sopova E, Joodmardi E, Yoshitake T, Deng Q, Kehr J, Ericson J, Svenningsson P, Shupliakov O, Perlmann T. Laguna A, et al. Among authors: svenningsson p. Nat Neurosci. 2015 Jun;18(6):826-35. doi: 10.1038/nn.4004. Epub 2015 Apr 27. Nat Neurosci. 2015. PMID: 25915474
Absence of the Autophagy Adaptor SQSTM1/p62 Causes Childhood-Onset Neurodegeneration with Ataxia, Dystonia, and Gaze Palsy.
Haack TB, Ignatius E, Calvo-Garrido J, Iuso A, Isohanni P, Maffezzini C, Lönnqvist T, Suomalainen A, Gorza M, Kremer LS, Graf E, Hartig M, Berutti R, Paucar M, Svenningsson P, Stranneheim H, Brandberg G, Wedell A, Kurian MA, Hayflick SA, Venco P, Tiranti V, Strom TM, Dichgans M, Horvath R, Holinski-Feder E, Freyer C, Meitinger T, Prokisch H, Senderek J, Wredenberg A, Carroll CJ, Klopstock T. Haack TB, et al. Among authors: svenningsson p. Am J Hum Genet. 2016 Sep 1;99(3):735-743. doi: 10.1016/j.ajhg.2016.06.026. Epub 2016 Aug 18. Am J Hum Genet. 2016. PMID: 27545679 Free PMC article.
Genetic Variations and mRNA Expression of NRF2 in Parkinson's Disease.
Ran C, Wirdefeldt K, Brodin L, Ramezani M, Westerlund M, Xiang F, Anvret A, Willows T, Sydow O, Johansson A, Galter D, Svenningsson P, Belin AC. Ran C, et al. Among authors: svenningsson p. Parkinsons Dis. 2017;2017:4020198. doi: 10.1155/2017/4020198. Epub 2017 May 2. Parkinsons Dis. 2017. PMID: 28540099 Free PMC article.
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