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PARKIN is not required to sustain OXPHOS function in adult mammalian tissues.
Filograna R, Gerlach J, Choi HN, Rigoni G, Barbaro M, Oscarson M, Lee S, Tiklova K, Ringnér M, Koolmeister C, Wibom R, Riggare S, Nennesmo I, Perlmann T, Wredenberg A, Wedell A, Motori E, Svenningsson P, Larsson NG. Filograna R, et al. Among authors: perlmann t. NPJ Parkinsons Dis. 2024 Apr 29;10(1):93. doi: 10.1038/s41531-024-00707-0. NPJ Parkinsons Dis. 2024. PMID: 38684669 Free PMC article.
PRC2-mediated repression is essential to maintain identity and function of differentiated dopaminergic and serotonergic neurons.
Toskas K, Yaghmaeian-Salmani B, Skiteva O, Paslawski W, Gillberg L, Skara V, Antoniou I, Södersten E, Svenningsson P, Chergui K, Ringnér M, Perlmann T, Holmberg J. Toskas K, et al. Among authors: perlmann t. Sci Adv. 2022 Aug 26;8(34):eabo1543. doi: 10.1126/sciadv.abo1543. Epub 2022 Aug 26. Sci Adv. 2022. PMID: 36026451 Free PMC article.
Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons.
Kadkhodaei B, Ito T, Joodmardi E, Mattsson B, Rouillard C, Carta M, Muramatsu S, Sumi-Ichinose C, Nomura T, Metzger D, Chambon P, Lindqvist E, Larsson NG, Olson L, Björklund A, Ichinose H, Perlmann T. Kadkhodaei B, et al. Among authors: perlmann t. J Neurosci. 2009 Dec 16;29(50):15923-32. doi: 10.1523/JNEUROSCI.3910-09.2009. J Neurosci. 2009. PMID: 20016108 Free PMC article.
120 results