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Early, precise, and safe clinical evaluation of the pharmacodynamic effects of novel agents in the intact human tumor microenvironment.
Front Pharmacol. 2024 Apr 12;15:1367581. doi: 10.3389/fphar.2024.1367581. eCollection 2024.
Front Pharmacol. 2024.
PMID: 38681192
Free PMC article.
Voruciclib, a clinical stage oral CDK9 inhibitor, represses MCL-1 and sensitizes high-risk Diffuse Large B-cell Lymphoma to BCL2 inhibition.
Dey J, Deckwerth TL, Kerwin WS, Casalini JR, Merrell AJ, Grenley MO, Burns C, Ditzler SH, Dixon CP, Beirne E, Gillespie KC, Kleinman EF, Klinghoffer RA.
Dey J, et al. Among authors: gillespie kc.
Sci Rep. 2017 Dec 21;7(1):18007. doi: 10.1038/s41598-017-18368-w.
Sci Rep. 2017.
PMID: 29269870
Free PMC article.
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