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Incidences of colorectal adenomas and cancers under colonoscopy surveillance suggest an accelerated "Big Bang" pathway to CRC in three of the four Lynch syndromes.
Møller P, Haupt S, Ahadova A, Kloor M, Sampson JR, Sunde L, Seppälä T, Burn J, Bernstein I, Capella G, Evans DG, Lindblom A, Winship I, Macrae F, Katz L, Laish I, Vainer E, Monahan K, Half E, Horisberger K, da Silva LA, Heuveline V, Therkildsen C, Lautrup C, Klarskov LL, Cavestro GM, Möslein G, Hovig E, Dominguez-Valentin M. Møller P, et al. Among authors: kloor m. Hered Cancer Clin Pract. 2024 May 13;22(1):6. doi: 10.1186/s13053-024-00279-3. Hered Cancer Clin Pract. 2024. PMID: 38741120 Free PMC article.
Clinical significance of combined tumour-infiltrating lymphocytes and microsatellite instability status in colorectal cancer: a systematic review and network meta-analysis.
Wankhede D, Yuan T, Kloor M, Halama N, Brenner H, Hoffmeister M. Wankhede D, et al. Among authors: kloor m. Lancet Gastroenterol Hepatol. 2024 May 8:S2468-1253(24)00091-8. doi: 10.1016/S2468-1253(24)00091-8. Online ahead of print. Lancet Gastroenterol Hepatol. 2024. PMID: 38734024 Free article.
Using histopathology latent diffusion models as privacy-preserving dataset augmenters improves downstream classification performance.
Niehues JM, Müller-Franzes G, Schirris Y, Wagner SJ, Jendrusch M, Kloor M, Pearson AT, Muti HS, Hewitt KJ, Veldhuizen GP, Zigutyte L, Truhn D, Kather JN. Niehues JM, et al. Among authors: kloor m. Comput Biol Med. 2024 Jun;175:108410. doi: 10.1016/j.compbiomed.2024.108410. Epub 2024 Apr 4. Comput Biol Med. 2024. PMID: 38678938
Case Report: Long-Term Survival of a Patient with Cerebral Metastasized Ovarian Carcinoma Treated with a Personalized Peptide Vaccine and Anti-PD-1 Therapy.
Zelba H, Kyzirakos C, Kayser S, Shao B, Reinhardt A, Pieper N, Rabsteyn A, Döcker D, Armeanu-Ebinger S, Kloor M, Hadaschik D, Schulze M, Battke F, Golf A, Biskup S. Zelba H, et al. Among authors: kloor m. Vaccines (Basel). 2024 Apr 9;12(4):397. doi: 10.3390/vaccines12040397. Vaccines (Basel). 2024. PMID: 38675779 Free PMC article.
Frameshift mutations in peripheral blood as a biomarker for surveillance of lynch syndrome.
Song Y, Loomans-Kropp H, Baugher RN, Somerville B, Baxter SS, Kerr TD, Plona TM, Mellott SD, Young TB, Lawhorn HE, Wei L, Hu Q, Liu S, Hutson A, Pinto L, Potter JD, Sei S, Gelincik O, Lipkin SM, Gebert J, Kloor M, Shoemaker RH. Song Y, et al. Among authors: kloor m. J Natl Cancer Inst. 2024 Mar 11:djae060. doi: 10.1093/jnci/djae060. Online ahead of print. J Natl Cancer Inst. 2024. PMID: 38466935
MLH1 Promotor Hypermethylation in Colorectal and Endometrial Carcinomas from Patients with Lynch Syndrome.
Helderman NC, Andini KD, van Leerdam ME, van Hest LP, Hoekman DR, Ahadova A, Bajwa-Ten Broeke SW, Bosse T, van der Logt EMJ, Imhann F, Kloor M, Langers AMJ, Smit VTHBM, Terlouw D, van Wezel T, Morreau H, Nielsen M. Helderman NC, et al. Among authors: kloor m. J Mol Diagn. 2024 Feb;26(2):106-114. doi: 10.1016/j.jmoldx.2023.10.005. Epub 2023 Dec 5. J Mol Diagn. 2024. PMID: 38061582 Free article.
CpG-biomarkers in tumor tissue and prediction models for the survival of colorectal cancer: A systematic review and external validation study.
Yuan T, Edelmann D, Kather JN, Fan Z, Tagscherer KE, Roth W, Bewerunge-Hudler M, Brobeil A, Kloor M, Bläker H, Burwinkel B, Brenner H, Hoffmeister M. Yuan T, et al. Among authors: kloor m. Crit Rev Oncol Hematol. 2024 Jan;193:104199. doi: 10.1016/j.critrevonc.2023.104199. Epub 2023 Nov 11. Crit Rev Oncol Hematol. 2024. PMID: 37952858 Review.
205 results