Fischer R - Search Results

1

The pRb/RBL2-E2F1/4-GCN5 axis regulates cancer stem cell formation and G0 phase entry/exit by paracrine mechanisms.

Chang CH, Liu F, Militi S, Hester S, Nibhani R, Deng S, Dunford J, Rendek A, Soonawalla Z, Fischer R, Oppermann U, Pauklin S. Chang CH, et al. Among authors: fischer r. Nat Commun. 2024 Apr 27;15(1):3580. doi: 10.1038/s41467-024-47680-z. Nat Commun. 2024. PMID: 38678032 Free PMC article.

2

A TFEB nuclear export signal integrates amino acid supply and glucose availability.

Li L, Friedrichsen HJ, Andrews S, Picaud S, Volpon L, Ngeow K, Berridge G, Fischer R, Borden KLB, Filippakopoulos P, Goding CR. Li L, et al. Among authors: fischer r. Nat Commun. 2018 Jul 11;9(1):2685. doi: 10.1038/s41467-018-04849-7. Nat Commun. 2018. PMID: 29992949 Free PMC article.

3

A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes.

Zhang T, Wei G, Millard CJ, Fischer R, Konietzny R, Kessler BM, Schwabe JWR, Brockdorff N. Zhang T, et al. Among authors: fischer r. Nat Commun. 2018 Sep 18;9(1):3798. doi: 10.1038/s41467-018-06235-9. Nat Commun. 2018. PMID: 30228260 Free PMC article.

4

Bi-directional signaling by membrane-bound KitL induces proliferation and coordinates thymic endothelial cell and thymocyte expansion.

Buono M, Thézénas ML, Ceroni A, Fischer R, Nerlov C. Buono M, et al. Among authors: fischer r. Nat Commun. 2018 Nov 8;9(1):4685. doi: 10.1038/s41467-018-07024-0. Nat Commun. 2018. PMID: 30410062 Free PMC article.

5

Colorectal cancer liver metastatic growth depends on PAD4-driven citrullination of the extracellular matrix.

Yuzhalin AE, Gordon-Weeks AN, Tognoli ML, Jones K, Markelc B, Konietzny R, Fischer R, Muth A, O'Neill E, Thompson PR, Venables PJ, Kessler BM, Lim SY, Muschel RJ. Yuzhalin AE, et al. Among authors: fischer r. Nat Commun. 2018 Nov 14;9(1):4783. doi: 10.1038/s41467-018-07306-7. Nat Commun. 2018. PMID: 30429478 Free PMC article.

6

Defactinib inhibits PYK2 phosphorylation of IRF5 and reduces intestinal inflammation.

Ryzhakov G, Almuttaqi H, Corbin AL, Berthold DL, Khoyratty T, Eames HL, Bullers S, Pearson C, Ai Z, Zec K, Bonham S, Fischer R, Jostins-Dean L, Travis SPL, Kessler BM, Udalova IA. Ryzhakov G, et al. Among authors: fischer r. Nat Commun. 2021 Nov 18;12(1):6702. doi: 10.1038/s41467-021-27038-5. Nat Commun. 2021. PMID: 34795257 Free PMC article.

7

T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles.

Céspedes PF, Jainarayanan A, Fernández-Messina L, Valvo S, Saliba DG, Kurz E, Kvalvaag A, Chen L, Ganskow C, Colin-York H, Fritzsche M, Peng Y, Dong T, Johnson E, Siller-Farfán JA, Dushek O, Sezgin E, Peacock B, Law A, Aubert D, Engledow S, Attar M, Hester S, Fischer R, Sánchez-Madrid F, Dustin ML. Céspedes PF, et al. Among authors: fischer r. Nat Commun. 2022 Jun 16;13(1):3460. doi: 10.1038/s41467-022-31160-3. Nat Commun. 2022. PMID: 35710644 Free PMC article.

8

Mapping autophagosome contents identifies interleukin-7 receptor-α as a key cargo modulating CD4+ T cell proliferation.

Zhou D, Borsa M, Puleston DJ, Zellner S, Capera J, Sanderson S, Schifferer M, Hester SS, Ge X, Fischer R, Jostins L, Behrends C, Alsaleh G, Simon AK. Zhou D, et al. Among authors: fischer r. Nat Commun. 2022 Sep 2;13(1):5174. doi: 10.1038/s41467-022-32718-x. Nat Commun. 2022. PMID: 36055998 Free PMC article.

9

Loss of FAM111B protease mutated in hereditary fibrosing poikiloderma negatively regulates telomere length.

Kliszczak M, Moralli D, Jankowska JD, Bryjka P, Subha Meem L, Goncalves T, Hester SS, Fischer R, Clynes D, Green CM. Kliszczak M, et al. Among authors: fischer r. Front Cell Dev Biol. 2023 Jun 5;11:1175069. doi: 10.3389/fcell.2023.1175069. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 37342232 Free PMC article.

10

Biallelic FBXW7 knockout induces AKAP8-mediated DNA damage in neighbouring wildtype cells.

Chan DKH, Mandal A, Hester S, Yu Z, Higgins GS, Kessler BM, Fischer R, Buczacki SJA. Chan DKH, et al. Among authors: fischer r. Cell Death Discov. 2023 Jun 29;9(1):200. doi: 10.1038/s41420-023-01494-y. Cell Death Discov. 2023. PMID: 37386001 Free PMC article.

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