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Synthesis of a new 2-prenylated quinoline as potential drug for metabolic syndrome with pan-PPAR activity and anti-inflammatory effects.
Villarroel-Vicente C, García A, Zibar K, Schiel MA, Ferri J, Hennuyer N, Enriz RD, Staels B, Cortes D, Cabedo N. Villarroel-Vicente C, et al. Among authors: cabedo n. Bioorg Med Chem Lett. 2024 Jul 1;106:129770. doi: 10.1016/j.bmcl.2024.129770. Epub 2024 Apr 26. Bioorg Med Chem Lett. 2024. PMID: 38677560 Free article.
Synthesis of benzopyran derivatives as PPARα and/or PPARγ activators.
Bermejo A, Barrachina I, El Aouad N, Franck X, Chahboune N, Andreu I, Figadère B, Vila L, Hennuyer N, Staels B, Dacquet C, Caignard DH, Sanz MJ, Cortes D, Cabedo N. Bermejo A, et al. Among authors: cabedo n. Bioorg Med Chem. 2019 Dec 15;27(24):115162. doi: 10.1016/j.bmc.2019.115162. Epub 2019 Oct 30. Bioorg Med Chem. 2019. PMID: 31703893
Synthesis of 2-Prenylated Alkoxylated Benzopyrans by Horner-Wadsworth-Emmons Olefination with PPARα/γ Agonist Activity.
García A, Vila L, Marín P, Bernabeu Á, Villarroel-Vicente C, Hennuyer N, Staels B, Franck X, Figadère B, Cabedo N, Cortes D. García A, et al. Among authors: cabedo n. ACS Med Chem Lett. 2021 Oct 6;12(11):1783-1786. doi: 10.1021/acsmedchemlett.1c00400. eCollection 2021 Nov 11. ACS Med Chem Lett. 2021. PMID: 34795868 Free PMC article.
Anti-inflammatory effects and improved metabolic derangements in ob/ob mice by a newly synthesized prenylated benzopyran with pan-PPAR activity.
Marques P, Villarroel-Vicente C, Collado A, García A, Vila L, Duplan I, Hennuyer N, Garibotto F, Enriz RD, Dacquet C, Staels B, Piqueras L, Cortes D, Sanz MJ, Cabedo N. Marques P, et al. Among authors: cabedo n. Pharmacol Res. 2023 Jan;187:106638. doi: 10.1016/j.phrs.2022.106638. Epub 2022 Dec 28. Pharmacol Res. 2023. PMID: 36586645 Free article.
New antitumoral acetogenin 'Guanacone type' derivatives: isolation and bioactivity. Molecular dynamics simulation of diacetyl-guanacone.
Barrachina I, Royo I, Baldoni HA, Chahboune N, Suvire F, DePedro N, Zafra-Polo MC, Bermejo A, El Aouad N, Cabedo N, Saez J, Tormo JR, Enriz RD, Cortes D. Barrachina I, et al. Among authors: cabedo n. Bioorg Med Chem. 2007 Jul 1;15(13):4369-81. doi: 10.1016/j.bmc.2007.04.039. Epub 2007 Apr 25. Bioorg Med Chem. 2007. PMID: 17482824
Tetrahydroisoquinolines as dopaminergic ligands: 1-Butyl-7-chloro-6-hydroxy-tetrahydroisoquinoline, a new compound with antidepressant-like activity in mice.
Berenguer I, El Aouad N, Andujar S, Romero V, Suvire F, Freret T, Bermejo A, Ivorra MD, Enriz RD, Boulouard M, Cabedo N, Cortes D. Berenguer I, et al. Among authors: cabedo n. Bioorg Med Chem. 2009 Jul 15;17(14):4968-80. doi: 10.1016/j.bmc.2009.05.079. Epub 2009 Jun 6. Bioorg Med Chem. 2009. PMID: 19540762
Synthesis of new antimicrobial pyrrolo[2,1-a]isoquinolin-3-ones.
Moreno L, Párraga J, Galán A, Cabedo N, Primo J, Cortes D. Moreno L, et al. Among authors: cabedo n. Bioorg Med Chem. 2012 Nov 15;20(22):6589-97. doi: 10.1016/j.bmc.2012.09.033. Epub 2012 Sep 24. Bioorg Med Chem. 2012. PMID: 23062823
50 results