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Multi-tissue profiling of oxylipins reveal a conserved up-regulation of epoxide:diol ratio that associates with white adipose tissue inflammation and liver steatosis in obesity.
Hateley C, Olona A, Halliday L, Edin ML, Ko JH, Forlano R, Terra X, Lih FB, Beltrán-Debón R, Manousou P, Purkayastha S, Moorthy K, Thursz MR, Zhang G, Goldin RD, Zeldin DC, Petretto E, Behmoaras J. Hateley C, et al. Among authors: thursz mr. EBioMedicine. 2024 May;103:105127. doi: 10.1016/j.ebiom.2024.105127. Epub 2024 Apr 26. EBioMedicine. 2024. PMID: 38677183 Free PMC article.
Dysregulated anti-oxidant signalling and compromised mitochondrial integrity negatively influence regulatory T cell function and viability in liver disease.
Vaikunthanathan T, Landmann E, Correa DM, Romano M, Trevelin SC, Peng Q, Crespo E, Corrado M, Lozano JJ, Pearce EL, Perpinan E, Zoccarato A, Siew L, Edwards-Hicks J, Khan R, Luu NT, Thursz MR, Newsome PN, Martinez-Llordella M, Shah N, Lechler RI, Shah AM, Sanchez-Fueyo A, Lombardi G, Safinia N. Vaikunthanathan T, et al. Among authors: thursz mr. EBioMedicine. 2023 Sep;95:104778. doi: 10.1016/j.ebiom.2023.104778. Epub 2023 Aug 30. EBioMedicine. 2023. PMID: 37657135 Free PMC article.
Clinical characteristics and outcomes of patients with cirrhosis and hepatocellular carcinoma in The Gambia, west Africa: a prospective cohort study.
Ndow G, Vo-Quang E, Shimakawa Y, Ceesay A, Tamba S, Njai HF, Bojang L, Hateley C, Takao Y, Opoku E, Warsop Z, Ingiliz P, D'Alessandro U, Chemin I, Mendy M, Thursz M, Njie R, Lemoine M. Ndow G, et al. Lancet Glob Health. 2023 Sep;11(9):e1383-e1392. doi: 10.1016/S2214-109X(23)00263-2. Epub 2023 Jul 27. Lancet Glob Health. 2023. PMID: 37517420 Free article.
Immune Checkpoint Inhibitor-Induced Liver Injury.
Gudd CLC, Sheth R, Thursz MR, Triantafyllou E, Possamai LA. Gudd CLC, et al. Among authors: thursz mr. Semin Liver Dis. 2023 Nov;43(4):402-417. doi: 10.1055/s-0043-1776761. Epub 2023 Dec 15. Semin Liver Dis. 2023. PMID: 38101418 Review.
161 results