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Comprehensive Ocular and Systemic Safety Evaluation of Polysialic Acid-Decorated Immune Modulating Therapeutic Nanoparticles (PolySia-NPs) to Support Entry into First-in-Human Clinical Trials.
Krishnan A, Callanan DG, Sendra VG, Lad A, Christian S, Earla R, Khanehzar A, Tolentino AJ, Vailoces VAS, Greene MK, Scott CJ, Kunimoto DY, Hassan TS, Genead MA, Tolentino MJ. Krishnan A, et al. Among authors: greene mk. Pharmaceuticals (Basel). 2024 Apr 9;17(4):481. doi: 10.3390/ph17040481. Pharmaceuticals (Basel). 2024. PMID: 38675441 Free PMC article.
PolySialic acid-nanoparticles inhibit macrophage mediated inflammation through Siglec agonism: a potential treatment for age related macular degeneration.
Krishnan A, Sendra VG, Patel D, Lad A, Greene MK, Smyth P, Gallaher SA, Herron ÚM, Scott CJ, Genead M, Tolentino M. Krishnan A, et al. Among authors: greene mk. Front Immunol. 2023 Nov 16;14:1237016. doi: 10.3389/fimmu.2023.1237016. eCollection 2023. Front Immunol. 2023. PMID: 38045700 Free PMC article.
Nanoencapsulation of MDM2 Inhibitor RG7388 and Class-I HDAC Inhibitor Entinostat Enhances their Therapeutic Potential Through Synergistic Antitumor Effects and Reduction of Systemic Toxicity.
Abed A, Greene MK, Alsa'd AA, Lees A, Hindley A, Longley DB, McDade SS, Scott CJ. Abed A, et al. Among authors: greene mk. Mol Pharm. 2024 Mar 4;21(3):1246-1255. doi: 10.1021/acs.molpharmaceut.3c00926. Epub 2024 Feb 9. Mol Pharm. 2024. PMID: 38334409 Free PMC article.
DR5-targeted, chemotherapeutic drug-loaded nanoparticles induce apoptosis and tumor regression in pancreatic cancer in vivo models.
Johnston MC, Nicoll JA, Redmond KM, Smyth P, Greene MK, McDaid WJ, Chan DKW, Crawford N, Stott KJ, Fox JP, Straubinger NL, Roche S, Clynes M, Straubinger RM, Longley DB, Scott CJ. Johnston MC, et al. Among authors: greene mk. J Control Release. 2020 Aug 10;324:610-619. doi: 10.1016/j.jconrel.2020.05.046. Epub 2020 Jun 3. J Control Release. 2020. PMID: 32504778 Free PMC article.
30 results