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Combined Metabolic Activators with Different NAD+ Precursors Improve Metabolic Functions in the Animal Models of Neurodegenerative Diseases.
Altay O, Yang H, Yildirim S, Bayram C, Bolat I, Oner S, Tozlu OO, Arslan ME, Hacimuftuoglu A, Shoaie S, Zhang C, Borén J, Uhlén M, Turkez H, Mardinoglu A. Altay O, et al. Among authors: boren j. Biomedicines. 2024 Apr 22;12(4):927. doi: 10.3390/biomedicines12040927. Biomedicines. 2024. PMID: 38672280 Free PMC article.
The Potential Use of Metabolic Cofactors in Treatment of NAFLD.
Mardinoglu A, Ural D, Zeybel M, Yuksel HH, Uhlén M, Borén J. Mardinoglu A, et al. Among authors: boren j. Nutrients. 2019 Jul 12;11(7):1578. doi: 10.3390/nu11071578. Nutrients. 2019. PMID: 31336926 Free PMC article. Review.
Addressing the heterogeneity in liver diseases using biological networks.
Lam S, Doran S, Yuksel HH, Altay O, Turkez H, Nielsen J, Boren J, Uhlen M, Mardinoglu A. Lam S, et al. Among authors: boren j. Brief Bioinform. 2021 Mar 22;22(2):1751-1766. doi: 10.1093/bib/bbaa002. Brief Bioinform. 2021. PMID: 32201876 Free PMC article. Review.
A systems biology approach for studying neurodegenerative diseases.
Lam S, Bayraktar A, Zhang C, Turkez H, Nielsen J, Boren J, Shoaie S, Uhlen M, Mardinoglu A. Lam S, et al. Among authors: boren j. Drug Discov Today. 2020 Jul;25(7):1146-1159. doi: 10.1016/j.drudis.2020.05.010. Epub 2020 May 19. Drug Discov Today. 2020. PMID: 32442631 Review.
Combined Metabolic Activators Accelerates Recovery in Mild-to-Moderate COVID-19.
Altay O, Arif M, Li X, Yang H, Aydın M, Alkurt G, Kim W, Akyol D, Zhang C, Dinler-Doganay G, Turkez H, Shoaie S, Nielsen J, Borén J, Olmuscelik O, Doganay L, Uhlén M, Mardinoglu A. Altay O, et al. Among authors: boren j. Adv Sci (Weinh). 2021 Sep;8(17):e2101222. doi: 10.1002/advs.202101222. Epub 2021 Jun 28. Adv Sci (Weinh). 2021. PMID: 34180141 Free PMC article. Clinical Trial.
Combined metabolic activators therapy ameliorates liver fat in nonalcoholic fatty liver disease patients.
Zeybel M, Altay O, Arif M, Li X, Yang H, Fredolini C, Akyildiz M, Saglam B, Gonenli MG, Ural D, Kim W, Schwenk JM, Zhang C, Shoaie S, Nielsen J, Uhlén M, Borén J, Mardinoglu A. Zeybel M, et al. Among authors: boren j. Mol Syst Biol. 2021 Oct;17(10):e10459. doi: 10.15252/msb.202110459. Mol Syst Biol. 2021. PMID: 34694070 Free PMC article. Clinical Trial.
Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning.
Zhang C, Shi M, Kim W, Arif M, Klevstig M, Li X, Yang H, Bayram C, Bolat I, Tozlu ÖÖ, Hacımuftuoglu A, Yıldırım S, Sebhaoui J, Iqbal S, Wei Y, Shi X, Nielsen J, Turkez H, Uhlen M, Boren J, Mardinoglu A. Zhang C, et al. Among authors: boren j. EBioMedicine. 2022 Sep;83:104214. doi: 10.1016/j.ebiom.2022.104214. Epub 2022 Aug 18. EBioMedicine. 2022. PMID: 35988463 Free PMC article.
Ellagic Acid and Its Metabolites as Potent and Selective Allosteric Inhibitors of Liver Pyruvate Kinase.
Battisti UM, Gao C, Akladios F, Kim W, Yang H, Bayram C, Bolat I, Kiliclioglu M, Yuksel N, Tozlu OO, Zhang C, Sebhaoui J, Iqbal S, Shoaie S, Hacimuftuoglu A, Yildirim S, Turkez H, Uhlen M, Boren J, Mardinoglu A, Grøtli M. Battisti UM, et al. Among authors: boren j. Nutrients. 2023 Jan 22;15(3):577. doi: 10.3390/nu15030577. Nutrients. 2023. PMID: 36771285 Free PMC article.
478 results