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Mucosal prime-boost immunization with live murine pneumonia virus-vectored SARS-CoV-2 vaccine is protective in macaques.
Kaiser JA, Nelson CE, Liu X, Park HS, Matsuoka Y, Luongo C, Santos C, Ahlers LRH, Herbert R, Moore IN, Wilder-Kofie T, Moore R, Walker A, Yang L, Munir S, Teng IT, Kwong PD, Dowdell K, Nguyen H, Kim J, Cohen JI, Johnson RF, Garza NL, Via LE, Barber DL, Buchholz UJ, Le Nouën C. Kaiser JA, et al. Among authors: luongo c. Nat Commun. 2024 Apr 26;15(1):3553. doi: 10.1038/s41467-024-47784-6. Nat Commun. 2024. PMID: 38670948 Free PMC article.
A single intranasal dose of a live-attenuated parainfluenza virus-vectored SARS-CoV-2 vaccine is protective in hamsters.
Liu X, Luongo C, Matsuoka Y, Park HS, Santos C, Yang L, Moore IN, Afroz S, Johnson RF, Lafont BAP, Martens C, Best SM, Munster VJ, Hollý J, Yewdell JW, Le Nouën C, Munir S, Buchholz UJ. Liu X, et al. Among authors: luongo c. Proc Natl Acad Sci U S A. 2021 Dec 14;118(50):e2109744118. doi: 10.1073/pnas.2109744118. Proc Natl Acad Sci U S A. 2021. PMID: 34876520 Free PMC article.
Intranasal pediatric parainfluenza virus-vectored SARS-CoV-2 vaccine candidate is protective in macaques.
Nouën CL, Nelson CE, Liu X, Park HS, Matsuoka Y, Luongo C, Santos C, Yang L, Herbert R, Castens A, Moore IN, Wilder-Kofie T, Moore R, Walker A, Zhang P, Lusso P, Johnson RF, Garza NL, Via LE, Munir S, Barber D, Buchholz UJ. Nouën CL, et al. Among authors: luongo c. bioRxiv [Preprint]. 2022 May 23:2022.05.21.492923. doi: 10.1101/2022.05.21.492923. bioRxiv. 2022. PMID: 35665011 Free PMC article. Updated. Preprint.
Intranasal pediatric parainfluenza virus-vectored SARS-CoV-2 vaccine is protective in monkeys.
Le Nouën C, Nelson CE, Liu X, Park HS, Matsuoka Y, Luongo C, Santos C, Yang L, Herbert R, Castens A, Moore IN, Wilder-Kofie T, Moore R, Walker A, Zhang P, Lusso P, Johnson RF, Garza NL, Via LE, Munir S, Barber DL, Buchholz UJ. Le Nouën C, et al. Among authors: luongo c. Cell. 2022 Dec 8;185(25):4811-4825.e17. doi: 10.1016/j.cell.2022.11.006. Epub 2022 Nov 10. Cell. 2022. PMID: 36423629 Free PMC article.
Live-attenuated pediatric parainfluenza vaccine expressing 6P-stabilized SARS-CoV-2 spike protein is protective against SARS-CoV-2 variants in hamsters.
Liu X, Park HS, Matsuoka Y, Santos C, Yang L, Luongo C, Moore IN, Johnson RF, Garza NL, Zhang P, Lusso P, Best SM, Buchholz UJ, Le Nouën C. Liu X, et al. Among authors: luongo c. bioRxiv [Preprint]. 2022 Dec 13:2022.12.12.520032. doi: 10.1101/2022.12.12.520032. bioRxiv. 2022. PMID: 36561185 Free PMC article. Updated. Preprint.
Mucosal prime-boost immunization with live murine pneumonia virus-vectored SARS-CoV-2 vaccine is protective in macaques.
Buchholz U, Kaiser J, Nelson C, Liu X, Park HS, Matsuoka Y, Luongo C, Santos C, Ahlers L, Herbert R, Moore I, Wilder-Kofie T, Moore R, Walker A, Lijuan Y, Munir S, Teng IT, Kwong P, Dowdell K, Nguyen H, Kim J, Cohen J, Johnson RF, Garza N, Via L, Barber D, LE Nouen C. Buchholz U, et al. Among authors: luongo c. Res Sq [Preprint]. 2023 Sep 13:rs.3.rs-3278289. doi: 10.21203/rs.3.rs-3278289/v1. Res Sq. 2023. PMID: 37790295 Free PMC article. Updated. Preprint.
Respiratory syncytial virus modified by deletions of the NS2 gene and amino acid S1313 of the L polymerase protein is a temperature-sensitive, live-attenuated vaccine candidate that is phenotypically stable at physiological temperature.
Luongo C, Winter CC, Collins PL, Buchholz UJ. Luongo C, et al. J Virol. 2013 Feb;87(4):1985-96. doi: 10.1128/JVI.02769-12. Epub 2012 Dec 12. J Virol. 2013. PMID: 23236065 Free PMC article.
In previous work to develop point mutations in RSV with improved genetic stability, we observed that an attenuating mutation at amino acid position 1321 in the L polymerase protein was subject to deattenuation by a spontaneous second-site compensatory mutation at position 1313 ( …
In previous work to develop point mutations in RSV with improved genetic stability, we observed that an attenuating mutation at amino acid p …
178 results