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Axon guidance cue SEMA3A promotes the aggressive phenotype of basal-like PDAC.
Lupo F, Pezzini F, Pasini D, Fiorini E, Adamo A, Veghini L, Bevere M, Frusteri C, Delfino P, D'agosto S, Andreani S, Piro G, Malinova A, Wang T, De Sanctis F, Lawlor RT, Hwang CI, Carbone C, Amelio I, Bailey P, Bronte V, Tuveson D, Scarpa A, Ugel S, Corbo V. Lupo F, et al. Among authors: scarpa a. Gut. 2024 Apr 26:gutjnl-2023-329807. doi: 10.1136/gutjnl-2023-329807. Online ahead of print. Gut. 2024. PMID: 38670629 Free article.
Loss of FGFR4 promotes the malignant phenotype of PDAC.
D'Agosto S, Pezzini F, Veghini L, Delfino P, Fiorini C, Temgue Tane GD, Del Curatolo A, Vicentini C, Ferrari G, Pasini D, Andreani S, Lupo F, Fiorini E, Lorenzon G, Lawlor RT, Rusev B, Malinova A, Luchini C, Milella M, Sereni E, Pea A, Bassi C, Bailey P, Scarpa A, Bria E, Corbo V. D'Agosto S, et al. Among authors: scarpa a. Oncogene. 2022 Sep;41(38):4371-4384. doi: 10.1038/s41388-022-02432-5. Epub 2022 Aug 13. Oncogene. 2022. PMID: 35963908 Free PMC article.
Lysosomal lipid switch sensitises to nutrient deprivation and mTOR targeting in pancreatic cancer.
De Santis MC, Gozzelino L, Margaria JP, Costamagna A, Ratto E, Gulluni F, Di Gregorio E, Mina E, Lorito N, Bacci M, Lattanzio R, Sala G, Cappello P, Novelli F, Giovannetti E, Vicentini C, Andreani S, Delfino P, Corbo V, Scarpa A, Porporato PE, Morandi A, Hirsch E, Martini M. De Santis MC, et al. Among authors: scarpa a. Gut. 2023 Feb;72(2):360-371. doi: 10.1136/gutjnl-2021-325117. Epub 2022 May 27. Gut. 2023. PMID: 35623884 Free PMC article.
Preclinical Modelling of PDA: Is Organoid the New Black?
D'Agosto S, Andreani S, Scarpa A, Corbo V. D'Agosto S, et al. Among authors: scarpa a. Int J Mol Sci. 2019 Jun 5;20(11):2766. doi: 10.3390/ijms20112766. Int J Mol Sci. 2019. PMID: 31195689 Free PMC article. Review.
Immunosuppression by monocytic myeloid-derived suppressor cells in patients with pancreatic ductal carcinoma is orchestrated by STAT3.
Trovato R, Fiore A, Sartori S, Canè S, Giugno R, Cascione L, Paiella S, Salvia R, De Sanctis F, Poffe O, Anselmi C, Hofer F, Sartoris S, Piro G, Carbone C, Corbo V, Lawlor R, Solito S, Pinton L, Mandruzzato S, Bassi C, Scarpa A, Bronte V, Ugel S. Trovato R, et al. Among authors: scarpa a. J Immunother Cancer. 2019 Sep 18;7(1):255. doi: 10.1186/s40425-019-0734-6. J Immunother Cancer. 2019. PMID: 31533831 Free PMC article.
Intratumoral injection of TLR9 agonist promotes an immunopermissive microenvironment transition and causes cooperative antitumor activity in combination with anti-PD1 in pancreatic cancer.
Carbone C, Piro G, Agostini A, Delfino P, De Sanctis F, Nasca V, Spallotta F, Sette C, Martini M, Ugel S, Corbo V, Cappello P, Bria E, Scarpa A, Tortora G. Carbone C, et al. Among authors: scarpa a. J Immunother Cancer. 2021 Sep;9(9):e002876. doi: 10.1136/jitc-2021-002876. J Immunother Cancer. 2021. PMID: 34479922 Free PMC article.
CXCR1/2 dual-inhibitor ladarixin reduces tumour burden and promotes immunotherapy response in pancreatic cancer.
Piro G, Carbone C, Agostini A, Esposito A, De Pizzol M, Novelli R, Allegretti M, Aramini A, Caggiano A, Granitto A, De Sanctis F, Ugel S, Corbo V, Martini M, Lawlor RT, Scarpa A, Tortora G. Piro G, et al. Among authors: scarpa a. Br J Cancer. 2023 Jan;128(2):331-341. doi: 10.1038/s41416-022-02028-6. Epub 2022 Nov 16. Br J Cancer. 2023. PMID: 36385556 Free PMC article.
1,277 results