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Enhanced Stat3 activation in POMC neurons provokes negative feedback inhibition of leptin and insulin signaling in obesity.
Ernst MB, Wunderlich CM, Hess S, Paehler M, Mesaros A, Koralov SB, Kleinridders A, Husch A, Münzberg H, Hampel B, Alber J, Kloppenburg P, Brüning JC, Wunderlich FT. Ernst MB, et al. Among authors: wunderlich cm, wunderlich ft. J Neurosci. 2009 Sep 16;29(37):11582-93. doi: 10.1523/JNEUROSCI.5712-08.2009. J Neurosci. 2009. PMID: 19759305 Free PMC article.
A microRNA screen reveals that elevated hepatic ectodysplasin A expression contributes to obesity-induced insulin resistance in skeletal muscle.
Awazawa M, Gabel P, Tsaousidou E, Nolte H, Krüger M, Schmitz J, Ackermann PJ, Brandt C, Altmüller J, Motameny S, Wunderlich FT, Kornfeld JW, Blüher M, Brüning JC. Awazawa M, et al. Among authors: wunderlich ft. Nat Med. 2017 Dec;23(12):1466-1473. doi: 10.1038/nm.4420. Epub 2017 Nov 6. Nat Med. 2017. PMID: 29106399
Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting.
Biglari N, Gaziano I, Schumacher J, Radermacher J, Paeger L, Klemm P, Chen W, Corneliussen S, Wunderlich CM, Sue M, Vollmar S, Klöckener T, Sotelo-Hitschfeld T, Abbasloo A, Edenhofer F, Reimann F, Gribble FM, Fenselau H, Kloppenburg P, Wunderlich FT, Brüning JC. Biglari N, et al. Among authors: wunderlich cm, wunderlich ft. Nat Neurosci. 2021 Jul;24(7):913-929. doi: 10.1038/s41593-021-00854-0. Epub 2021 May 17. Nat Neurosci. 2021. PMID: 34002087 Free PMC article.
Mechanisms of chronic JAK-STAT3-SOCS3 signaling in obesity.
Wunderlich CM, Hövelmeyer N, Wunderlich FT. Wunderlich CM, et al. Among authors: wunderlich ft. JAKSTAT. 2013 Apr 1;2(2):e23878. doi: 10.4161/jkst.23878. JAKSTAT. 2013. PMID: 24058813 Free PMC article. Review.
98 results