Zajac AJ - Search Results

1

Gfi1 controls the formation of effector CD8 T cells during chronic infection and cancer.

Ojo OA, Shen H, Ingram JT, Bonner JA, Welner RS, Lacaud G, Zajac AJ, Shi LZ. Ojo OA, et al. Among authors: zajac aj. bioRxiv [Preprint]. 2024 Apr 21:2024.04.18.579535. doi: 10.1101/2024.04.18.579535. bioRxiv. 2024. PMID: 38659890 Free PMC article. Preprint.

2

IL-21 deficiency influences CD8 T cell quality and recall responses following an acute viral infection.

Yi JS, Ingram JT, Zajac AJ. Yi JS, et al. Among authors: zajac aj. J Immunol. 2010 Oct 15;185(8):4835-45. doi: 10.4049/jimmunol.1001032. Epub 2010 Sep 15. J Immunol. 2010. PMID: 20844201 Free PMC article.

3

Exhausted CD8 T cells downregulate the IL-18 receptor and become unresponsive to inflammatory cytokines and bacterial co-infections.

Ingram JT, Yi JS, Zajac AJ. Ingram JT, et al. Among authors: zajac aj. PLoS Pathog. 2011 Sep;7(9):e1002273. doi: 10.1371/journal.ppat.1002273. Epub 2011 Sep 29. PLoS Pathog. 2011. PMID: 21980291 Free PMC article.

4

A Context-Dependent Role for IL-21 in Modulating the Differentiation, Distribution, and Abundance of Effector and Memory CD8 T Cell Subsets.

Tian Y, Cox MA, Kahan SM, Ingram JT, Bakshi RK, Zajac AJ. Tian Y, et al. Among authors: zajac aj. J Immunol. 2016 Mar 1;196(5):2153-66. doi: 10.4049/jimmunol.1401236. Epub 2016 Jan 29. J Immunol. 2016. PMID: 26826252 Free PMC article.

5

Intrinsic IL-2 production by effector CD8 T cells affects IL-2 signaling and promotes fate decisions, stemness, and protection.

Kahan SM, Bakshi RK, Ingram JT, Hendrickson RC, Lefkowitz EJ, Crossman DK, Harrington LE, Weaver CT, Zajac AJ. Kahan SM, et al. Among authors: zajac aj. Sci Immunol. 2022 Feb 11;7(68):eabl6322. doi: 10.1126/sciimmunol.abl6322. Epub 2022 Feb 11. Sci Immunol. 2022. PMID: 35148200 Free PMC article.

6

Virus-specific CD4 and CD8 T cell responses in the absence of Th1-associated transcription factors.

Mollo SB, Ingram JT, Kress RL, Zajac AJ, Harrington LE. Mollo SB, et al. Among authors: zajac aj. J Leukoc Biol. 2014 May;95(5):705-713. doi: 10.1189/jlb.0813429. Epub 2013 Nov 14. J Leukoc Biol. 2014. PMID: 24231259 Free PMC article.

7

Tfh-cell-derived interleukin 21 sustains effector CD8⁺ T cell responses during chronic viral infection.

Zander R, Kasmani MY, Chen Y, Topchyan P, Shen J, Zheng S, Burns R, Ingram J, Cui C, Joshi N, Craft J, Zajac A, Cui W. Zander R, et al. Immunity. 2022 Mar 8;55(3):475-493.e5. doi: 10.1016/j.immuni.2022.01.018. Epub 2022 Feb 24. Immunity. 2022. PMID: 35216666 Free PMC article.

8

IL-10-producing Tfh cells accumulate with age and link inflammation with age-related immune suppression.

Almanan M, Raynor J, Ogunsulire I, Malyshkina A, Mukherjee S, Hummel SA, Ingram JT, Saini A, Xie MM, Alenghat T, Way SS, Deepe GS Jr, Divanovic S, Singh H, Miraldi E, Zajac AJ, Dent AL, Hölscher C, Chougnet C, Hildeman DA. Almanan M, et al. Among authors: zajac aj. Sci Adv. 2020 Jul 29;6(31):eabb0806. doi: 10.1126/sciadv.abb0806. eCollection 2020 Jul. Sci Adv. 2020. PMID: 32832688 Free PMC article.

9

CD4⁺ T Cell Help Is Required for the Formation of a Cytolytic CD8⁺ T Cell Subset that Protects against Chronic Infection and Cancer.

Zander R, Schauder D, Xin G, Nguyen C, Wu X, Zajac A, Cui W. Zander R, et al. Immunity. 2019 Dec 17;51(6):1028-1042.e4. doi: 10.1016/j.immuni.2019.10.009. Epub 2019 Dec 3. Immunity. 2019. PMID: 31810883 Free PMC article.

10

Therapeutic vaccination against chronic viral infection: the importance of cooperation between CD4+ and CD8+ T cells.

Zajac AJ, Murali-Krishna K, Blattman JN, Ahmed R. Zajac AJ, et al. Curr Opin Immunol. 1998 Aug;10(4):444-9. doi: 10.1016/s0952-7915(98)80119-2. Curr Opin Immunol. 1998. PMID: 9722921 Review.

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