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Prophage-encoded methyltransferase drives adaptation of community-acquired methicillin-resistant Staphylococcus aureus.
Ulrich RJ, Podkowik M, Tierce R, Irnov I, Putzel G, Samhadaneh N, Lacey KA, Boff D, Morales SM, Makita S, Karagounis TK, Zwack EE, Zhou C, Kim R, Drlica K, Pironti A, van Bakel H, Torres VJ, Shopsin B. Ulrich RJ, et al. Among authors: boff d. bioRxiv [Preprint]. 2024 Apr 17:2024.04.17.589803. doi: 10.1101/2024.04.17.589803. bioRxiv. 2024. PMID: 38659881 Free PMC article. Preprint.
MRSA lineage USA300 isolated from bloodstream infections exhibit altered virulence regulation.
Dyzenhaus S, Sullivan MJ, Alburquerque B, Boff D, van de Guchte A, Chung M, Fulmer Y, Copin R, Ilmain JK, O'Keefe A, Altman DR, Stubbe FX, Podkowik M, Dupper AC, Shopsin B, van Bakel H, Torres VJ. Dyzenhaus S, et al. Among authors: boff d. Cell Host Microbe. 2023 Feb 8;31(2):228-242.e8. doi: 10.1016/j.chom.2022.12.003. Epub 2023 Jan 20. Cell Host Microbe. 2023. PMID: 36681080 Free PMC article.
Pegylated LyeTx I-b peptide is effective against carbapenem-resistant Acinetobacter baumannii in an in vivo model of pneumonia and shows reduced toxicity.
César Moreira Brito J, Gustavo Lima W, Magalhães Resende J, Cristina Sampaio de Assis D, Boff D, Nascimento Cardoso V, Almeida Amaral F, Maria Souza-Fagundes E, Odília Antunes Fernandes S, Elena de Lima M. César Moreira Brito J, et al. Among authors: boff d. Int J Pharm. 2021 Nov 20;609:121156. doi: 10.1016/j.ijpharm.2021.121156. Epub 2021 Oct 6. Int J Pharm. 2021. PMID: 34624440
Inhibition of Drug-Induced Liver Injury in Mice Using a Positively Charged Peptide That Binds DNA.
Marques PE, Vandendriessche S, de Oliveira THC, Crijns H, Lopes ME, Blanter M, Schuermans S, Yu K, Poosti F, Vanheule V, Janssens R, Boff D, Kungl AJ, Menezes GB, Teixeira MM, Proost P. Marques PE, et al. Among authors: boff d. Hepatol Commun. 2021 Oct;5(10):1737-1754. doi: 10.1002/hep4.1759. Epub 2021 Jul 1. Hepatol Commun. 2021. PMID: 34532999 Free PMC article.
Endogenous modification of the chemoattractant CXCL5 alters receptor usage and enhances its activity toward neutrophils and monocytes.
Metzemaekers M, Mortier A, Vacchini A, Boff D, Yu K, Janssens R, Farina FM, Milanesi S, Berghmans N, Pörtner N, Van Damme J, Allegretti M, Teixeira MM, Locati M, Borroni EM, Amaral FA, Proost P. Metzemaekers M, et al. Among authors: boff d. Sci Signal. 2021 Mar 9;14(673):eaax3053. doi: 10.1126/scisignal.aax3053. Sci Signal. 2021. PMID: 33688078
Shortened derivatives from native antimicrobial peptide LyeTx I: In vitro and in vivo biological activity assessment.
Fuscaldi LL, de Avelar Júnior JT, Dos Santos DM, Boff D, de Oliveira VLS, Gomes KAGG, Cruz RC, de Oliveira PL, Magalhães PP, Cisalpino PS, Farias LM, de Souza-Fagundes EM, Delp J, Leist M, Resende JM, Amaral FA, Pimenta AMC, Fernandes SOA, Cardoso VN, de Lima ME. Fuscaldi LL, et al. Among authors: boff d. Exp Biol Med (Maywood). 2021 Feb;246(4):414-425. doi: 10.1177/1535370220966963. Epub 2020 Nov 11. Exp Biol Med (Maywood). 2021. PMID: 33175610 Free PMC article.
Peroxynitrite Exposure of CXCL12 Impairs Monocyte, Lymphocyte and Endothelial Cell Chemotaxis, Lymphocyte Extravasation in vivo and Anti-HIV-1 Activity.
Janssens R, Boff D, Ruytinx P, Mortier A, Vanheule V, Larsen O, Daugvilaite V, Rosenkilde MM, Noppen S, Liekens S, Schols D, De Meester I, Opdenakker G, Struyf S, Teixeira MM, Amaral FA, Proost P. Janssens R, et al. Among authors: boff d. Front Immunol. 2018 Aug 28;9:1933. doi: 10.3389/fimmu.2018.01933. eCollection 2018. Front Immunol. 2018. PMID: 30233568 Free PMC article.
24 results