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Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells.
Toledo CM, Ding Y, Hoellerbauer P, Davis RJ, Basom R, Girard EJ, Lee E, Corrin P, Hart T, Bolouri H, Davison J, Zhang Q, Hardcastle J, Aronow BJ, Plaisier CL, Baliga NS, Moffat J, Lin Q, Li XN, Nam DH, Lee J, Pollard SM, Zhu J, Delrow JJ, Clurman BE, Olson JM, Paddison PJ. Toledo CM, et al. Among authors: paddison pj. Cell Rep. 2015 Dec 22;13(11):2425-2439. doi: 10.1016/j.celrep.2015.11.021. Epub 2015 Dec 7. Cell Rep. 2015. PMID: 26673326 Free PMC article.
Neural G0: a quiescent-like state found in neuroepithelial-derived cells and glioma.
O'Connor SA, Feldman HM, Arora S, Hoellerbauer P, Toledo CM, Corrin P, Carter L, Kufeld M, Bolouri H, Basom R, Delrow J, McFaline-Figueroa JL, Trapnell C, Pollard SM, Patel A, Paddison PJ, Plaisier CL. O'Connor SA, et al. Among authors: paddison pj. Mol Syst Biol. 2021 Jun;17(6):e9522. doi: 10.15252/msb.20209522. Mol Syst Biol. 2021. PMID: 34101353 Free PMC article.
WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma.
Mitchell K, Sprowls SA, Arora S, Shakya S, Silver DJ, Goins CM, Wallace L, Roversi G, Schafer RE, Kay K, Miller TE, Lauko A, Bassett J, Kashyap A, D'Amato Kass J, Mulkearns-Hubert EE, Johnson S, Alvarado J, Rich JN, Holland EC, Paddison PJ, Patel AP, Stauffer SR, Hubert CG, Lathia JD. Mitchell K, et al. Among authors: paddison pj. Genes Dev. 2023 Feb 1;37(3-4):86-102. doi: 10.1101/gad.349803.122. Epub 2023 Feb 2. Genes Dev. 2023. PMID: 36732025 Free PMC article.
Functional genomic analysis of adult and pediatric brain tumor isolates.
Hoellerbauer P, Biery MC, Arora S, Rao Y, Girard EJ, Mitchell K, Dighe P, Kufeld M, Kuppers DA, Herman JA, Holland EC, Soroceanu L, Vitanza NA, Olson JM, Pritchard JR, Paddison PJ. Hoellerbauer P, et al. Among authors: paddison pj. bioRxiv [Preprint]. 2023 Jan 6:2023.01.05.522885. doi: 10.1101/2023.01.05.522885. bioRxiv. 2023. PMID: 36711964 Free PMC article. Preprint.
59 results