Minakhin L - Search Results

1

tRNA anticodon cleavage by target-activated CRISPR-Cas13a effector.

Jain I, Kolesnik M, Kuznedelov K, Minakhin L, Morozova N, Shiriaeva A, Kirillov A, Medvedeva S, Livenskyi A, Kazieva L, Makarova KS, Koonin EV, Borukhov S, Severinov K, Semenova E. Jain I, et al. Among authors: minakhin l. Sci Adv. 2024 Apr 26;10(17):eadl0164. doi: 10.1126/sciadv.adl0164. Epub 2024 Apr 24. Sci Adv. 2024. PMID: 38657076 Free PMC article.

2

Kinetics of the CRISPR-Cas9 effector complex assembly and the role of 3'-terminal segment of guide RNA.

Mekler V, Minakhin L, Semenova E, Kuznedelov K, Severinov K. Mekler V, et al. Among authors: minakhin l. Nucleic Acids Res. 2016 Apr 7;44(6):2837-45. doi: 10.1093/nar/gkw138. Epub 2016 Mar 3. Nucleic Acids Res. 2016. PMID: 26945042 Free PMC article.

3

C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector.

Abudayyeh OO, Gootenberg JS, Konermann S, Joung J, Slaymaker IM, Cox DB, Shmakov S, Makarova KS, Semenova E, Minakhin L, Severinov K, Regev A, Lander ES, Koonin EV, Zhang F. Abudayyeh OO, et al. Among authors: minakhin l. Science. 2016 Aug 5;353(6299):aaf5573. doi: 10.1126/science.aaf5573. Epub 2016 Jun 2. Science. 2016. PMID: 27256883 Free PMC article.

4

Defining the seed sequence of the Cas12b CRISPR-Cas effector complex.

Jain I, Minakhin L, Mekler V, Sitnik V, Rubanova N, Severinov K, Semenova E. Jain I, et al. Among authors: minakhin l. RNA Biol. 2019 Apr;16(4):413-422. doi: 10.1080/15476286.2018.1495492. Epub 2018 Aug 17. RNA Biol. 2019. PMID: 30022698 Free PMC article.

5

CRISPR-Cas molecular beacons as tool for studies of assembly of CRISPR-Cas effector complexes and their interactions with DNA.

Mekler V, Kuznedelov K, Minakhin L, Murugan K, Sashital DG, Severinov K. Mekler V, et al. Among authors: minakhin l. Methods Enzymol. 2019;616:337-363. doi: 10.1016/bs.mie.2018.10.026. Epub 2018 Dec 1. Methods Enzymol. 2019. PMID: 30691650 Free PMC article.

6

Transcription regulation by bacteriophage T4 AsiA.

Minakhin L, Severinov K. Minakhin L, et al. Protein Expr Purif. 2005 May;41(1):1-8. doi: 10.1016/j.pep.2004.09.019. Protein Expr Purif. 2005. PMID: 15802215 Review.

7

Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems.

Shmakov S, Abudayyeh OO, Makarova KS, Wolf YI, Gootenberg JS, Semenova E, Minakhin L, Joung J, Konermann S, Severinov K, Zhang F, Koonin EV. Shmakov S, et al. Among authors: minakhin l. Mol Cell. 2015 Nov 5;60(3):385-97. doi: 10.1016/j.molcel.2015.10.008. Epub 2015 Oct 22. Mol Cell. 2015. PMID: 26593719 Free PMC article.

8

Mechanism of duplex DNA destabilization by RNA-guided Cas9 nuclease during target interrogation.

Mekler V, Minakhin L, Severinov K. Mekler V, et al. Among authors: minakhin l. Proc Natl Acad Sci U S A. 2017 May 23;114(21):5443-5448. doi: 10.1073/pnas.1619926114. Epub 2017 May 8. Proc Natl Acad Sci U S A. 2017. PMID: 28484024 Free PMC article.

9

On the role of the Escherichia coli RNA polymerase sigma 70 region 4.2 and alpha-subunit C-terminal domains in promoter complex formation on the extended -10 galP1 promoter.

Minakhin L, Severinov K. Minakhin L, et al. J Biol Chem. 2003 Aug 8;278(32):29710-8. doi: 10.1074/jbc.M304906200. Epub 2003 Jun 11. J Biol Chem. 2003. PMID: 12801925 Free article.

10

Coupling of downstream RNA polymerase-promoter interactions with formation of catalytically competent transcription initiation complex.

Mekler V, Minakhin L, Borukhov S, Mustaev A, Severinov K. Mekler V, et al. Among authors: minakhin l. J Mol Biol. 2014 Dec 12;426(24):3973-3984. doi: 10.1016/j.jmb.2014.10.005. Epub 2014 Oct 13. J Mol Biol. 2014. PMID: 25311862 Free PMC article.

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