Siebinga H - Search Results

1

Quantification of biochemical PSA dynamics after radioligand therapy with [¹⁷⁷Lu]Lu-PSMA-I&T using a population pharmacokinetic/pharmacodynamic model.

Siebinga H, de Wit-van der Veen BJ, de Vries-Huizing DMV, Vogel WV, Hendrikx JJMA, Huitema ADR. Siebinga H, et al. EJNMMI Phys. 2024 Apr 24;11(1):39. doi: 10.1186/s40658-024-00642-2. EJNMMI Phys. 2024. PMID: 38656678 Free PMC article.

2

The cycle effect quantified: reduced tumour uptake in subsequent cycles of [¹⁷⁷Lu]Lu-HA-DOTATATE during peptide receptor radionuclide therapy.

Siebinga H, Hendrikx JJMA, de Vries-Huizing DMV, Huitema ADR, de Wit-van der Veen BJ. Siebinga H, et al. Eur J Nucl Med Mol Imaging. 2024 Feb;51(3):820-827. doi: 10.1007/s00259-023-06463-2. Epub 2023 Oct 16. Eur J Nucl Med Mol Imaging. 2024. PMID: 37843598

3

Predicting [¹⁷⁷Lu]Lu-HA-DOTATATE kidney and tumor accumulation based on [⁶⁸Ga]Ga-HA-DOTATATE diagnostic imaging using semi-physiological population pharmacokinetic modeling.

Siebinga H, de Wit-van der Veen BJ, Beijnen JH, Stokkel MPM, Dorlo TPC, Huitema ADR, Hendrikx JJMA. Siebinga H, et al. EJNMMI Phys. 2023 Aug 24;10(1):48. doi: 10.1186/s40658-023-00565-4. EJNMMI Phys. 2023. PMID: 37615812 Free PMC article.

4

Predicting the effect of different folate doses on [⁶⁸Ga]Ga-PSMA-11 organ and tumor uptake using physiologically based pharmacokinetic modeling.

Siebinga H, Hendrikx JJMA, Huitema ADR, de Wit-van der Veen BJ. Siebinga H, et al. EJNMMI Res. 2023 Jun 15;13(1):60. doi: 10.1186/s13550-023-01008-y. EJNMMI Res. 2023. PMID: 37318681 Free PMC article.

5

Population pharmacokinetic dosimetry model using imaging data to assess variability in pharmacokinetics of ¹⁷⁷ Lu-PSMA-617 in prostate cancer patients.

Siebinga H, Privé BM, Peters SMB, Nagarajah J, Dorlo TPC, Huitema ADR, de Wit-van der Veen BJ, Hendrikx JJMA. Siebinga H, et al. CPT Pharmacometrics Syst Pharmacol. 2023 Aug;12(8):1060-1071. doi: 10.1002/psp4.12914. Epub 2023 Feb 9. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 36760133 Free PMC article.

6

A physiologically based pharmacokinetic model for [⁶⁸Ga]Ga-(HA-)DOTATATE to predict whole-body distribution and tumor sink effects in GEP-NET patients.

Siebinga H, de Wit-van der Veen BJ, Beijnen JH, Dorlo TPC, Huitema ADR, Hendrikx JJMA. Siebinga H, et al. EJNMMI Res. 2023 Feb 3;13(1):8. doi: 10.1186/s13550-023-00958-7. EJNMMI Res. 2023. PMID: 36735114 Free PMC article.

7

The effect of long-acting somatostatin analogues on the uptake of [¹⁷⁷Lu]Lu-HA-DOTATATE.

Veerman CHAM, Siebinga H, de Vries-Huizing DMV, Tesselaar MET, Hendrikx JJMA, Stokkel MPM, Aalbersberg EA. Veerman CHAM, et al. Among authors: siebinga h. Eur J Nucl Med Mol Imaging. 2023 Apr;50(5):1434-1441. doi: 10.1007/s00259-022-06094-z. Epub 2023 Jan 4. Eur J Nucl Med Mol Imaging. 2023. PMID: 36598536

8

Somatostatin receptor saturation after administration of high peptide amounts of [¹⁷⁷Lu]Lu-HA-DOTATATE: when enough is enough.

Siebinga H, Veerman CHAM, de Wit-van der Veen L, Stokkel MPM, Hendrikx JJMA, Aalbersberg EA. Siebinga H, et al. EJNMMI Res. 2022 Dec 14;12(1):74. doi: 10.1186/s13550-022-00946-3. EJNMMI Res. 2022. PMID: 36515683 Free PMC article.

9

Current use and future potential of (physiologically based) pharmacokinetic modelling of radiopharmaceuticals: a review.

Siebinga H, de Wit-van der Veen BJ, Stokkel MDM, Huitema ADR, Hendrikx JJMA. Siebinga H, et al. Theranostics. 2022 Nov 14;12(18):7804-7820. doi: 10.7150/thno.77279. eCollection 2022. Theranostics. 2022. PMID: 36451855 Free PMC article. Review.

10

The Impact of Peptide Amount on Tumor Uptake to Assess PSMA Receptor Saturation on ⁶⁸Ga-PSMA-11 PET/CT in Patients with Primary Prostate Cancer.

Siebinga H, Heuvel JO, Rijkhorst EJ, Hendrikx JJMA, de Wit-van der Veen BJ. Siebinga H, et al. J Nucl Med. 2023 Jan;64(1):63-68. doi: 10.2967/jnumed.122.264101. Epub 2022 Jun 9. J Nucl Med. 2023. PMID: 35680416 Free article.

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