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Sex-specific cardiovascular remodeling leads to a divergent sex-dependent development of heart failure in aged hypertensive rats.
Kovács Á, Zhazykbayeva S, Herwig M, Fülöp GÁ, Csípő T, Oláh N, Hassoun R, Budde H, Osman H, Kaçmaz M, Jaquet K, Priksz D, Juhász B, Akin I, Papp Z, Schmidt WE, Mügge A, El-Battrawy I, Tóth A, Hamdani N. Kovács Á, et al. Geroscience. 2024 Apr 24. doi: 10.1007/s11357-024-01160-w. Online ahead of print. Geroscience. 2024. PMID: 38656649
Oxidative stress and inflammation distinctly drive molecular mechanisms of diastolic dysfunction and remodeling in female and male heart failure with preserved ejection fraction rats.
Zhazykbayeva S, Hassoun R, Herwig M, Budde H, Kovács Á, Mannherz HG, El-Battrawy I, Tóth A, Schmidt WE, Mügge A, Hamdani N. Zhazykbayeva S, et al. Among authors: kovacs a. Front Cardiovasc Med. 2023 Jun 8;10:1157398. doi: 10.3389/fcvm.2023.1157398. eCollection 2023. Front Cardiovasc Med. 2023. PMID: 37363100 Free PMC article.
Renin overexpression leads to increased titin-based stiffness contributing to diastolic dysfunction in hypertensive mRen2 rats.
Kovács Á, Fülöp GÁ, Kovács A, Csípő T, Bódi B, Priksz D, Juhász B, Beke L, Hendrik Z, Méhes G, Granzier HL, Édes I, Fagyas M, Papp Z, Barta J, Tóth A. Kovács Á, et al. Am J Physiol Heart Circ Physiol. 2016 Jun 1;310(11):H1671-82. doi: 10.1152/ajpheart.00842.2015. Epub 2016 Apr 8. Am J Physiol Heart Circ Physiol. 2016. PMID: 27059079 Free article.
Enhanced Cardiomyocyte Function in Hypertensive Rats With Diastolic Dysfunction and Human Heart Failure Patients After Acute Treatment With Soluble Guanylyl Cyclase (sGC) Activator.
Kolijn D, Kovács Á, Herwig M, Lódi M, Sieme M, Alhaj A, Sandner P, Papp Z, Reusch PH, Haldenwang P, Falcão-Pires I, Linke WA, Jaquet K, Van Linthout S, Mügge A, Tschöpe C, Hamdani N. Kolijn D, et al. Among authors: kovacs a. Front Physiol. 2020 May 25;11:345. doi: 10.3389/fphys.2020.00345. eCollection 2020. Front Physiol. 2020. PMID: 32523538 Free PMC article.
Interventricular Differences of Signaling Pathways-Mediated Regulation of Cardiomyocyte Function in Response to High Oxidative Stress in the Post-Ischemic Failing Rat Heart.
Kovács Á, Herwig M, Budde H, Delalat S, Kolijn D, Bódi B, Hassoun R, Tangos M, Zhazykbayeva S, Balogh Á, Czuriga D, Van Linthout S, Tschöpe C, Dhalla NS, Mügge A, Tóth A, Papp Z, Barta J, Hamdani N. Kovács Á, et al. Antioxidants (Basel). 2021 Jun 16;10(6):964. doi: 10.3390/antiox10060964. Antioxidants (Basel). 2021. PMID: 34208541 Free PMC article.
The Interplay between S-Glutathionylation and Phosphorylation of Cardiac Troponin I and Myosin Binding Protein C in End-Stage Human Failing Hearts.
Budde H, Hassoun R, Tangos M, Zhazykbayeva S, Herwig M, Varatnitskaya M, Sieme M, Delalat S, Sultana I, Kolijn D, Gömöri K, Jarkas M, Lódi M, Jaquet K, Kovács Á, Mannherz HG, Sequeira V, Mügge A, Leichert LI, Sossalla S, Hamdani N. Budde H, et al. Among authors: kovacs a. Antioxidants (Basel). 2021 Jul 16;10(7):1134. doi: 10.3390/antiox10071134. Antioxidants (Basel). 2021. PMID: 34356367 Free PMC article.
Changes in the SARS-CoV-2 cellular receptor ACE2 levels in cardiovascular patients: a potential biomarker for the stratification of COVID-19 patients.
Fagyas M, Bánhegyi V, Úri K, Enyedi A, Lizanecz E, Mányiné IS, Mártha L, Fülöp GÁ, Radovits T, Pólos M, Merkely B, Kovács Á, Szilvássy Z, Ungvári Z, Édes I, Csanádi Z, Boczán J, Takács I, Szabó G, Balla J, Balla G, Seferovic P, Papp Z, Tóth A. Fagyas M, et al. Among authors: kovacs a. Geroscience. 2021 Oct;43(5):2289-2304. doi: 10.1007/s11357-021-00467-2. Epub 2021 Oct 21. Geroscience. 2021. PMID: 34674152 Free PMC article.
Nicotinic-acid derivative BGP-15 improves diastolic function in a rabbit model of atherosclerotic cardiomyopathy.
Priksz D, Lampe N, Kovacs A, Herwig M, Bombicz M, Varga B, Wilisicz T, Szilvassy J, Posa A, Kiss R, Gesztelyi R, Raduly A, Szekeres R, Sieme M, Papp Z, Toth A, Hamdani N, Szilvassy Z, Juhasz B. Priksz D, et al. Among authors: kovacs a. Br J Pharmacol. 2022 May;179(10):2240-2258. doi: 10.1111/bph.15749. Epub 2022 Feb 5. Br J Pharmacol. 2022. PMID: 34811751 Free article.
Ca2+/calmodulin-dependent protein kinase II and protein kinase G oxidation contributes to impaired sarcomeric proteins in hypertrophy model.
Gömöri K, Herwig M, Budde H, Hassoun R, Mostafi N, Zhazykbayeva S, Sieme M, Modi S, Szabados T, Pipis J, Farkas-Morvay N, Leprán I, Ágoston G, Baczkó I, Kovács Á, Mügge A, Ferdinandy P, Görbe A, Bencsik P, Hamdani N. Gömöri K, et al. Among authors: kovacs a. ESC Heart Fail. 2022 Aug;9(4):2585-2600. doi: 10.1002/ehf2.13973. Epub 2022 May 18. ESC Heart Fail. 2022. PMID: 35584900 Free PMC article.
2,268 results