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Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy.
Ward MA, Vangala JR, Kamber Kaya HE, Byers HA, Hosseini N, Diaz A, Cuervo AM, Kaushik S, Radhakrishnan SK. Ward MA, et al. Among authors: diaz a. J Cell Biol. 2024 Jun 3;223(6):e202306150. doi: 10.1083/jcb.202306150. Epub 2024 Apr 24. J Cell Biol. 2024. PMID: 38656405 Free PMC article.
Reciprocal regulation of chaperone-mediated autophagy and the circadian clock.
Juste YR, Kaushik S, Bourdenx M, Aflakpui R, Bandyopadhyay S, Garcia F, Diaz A, Lindenau K, Tu V, Krause GJ, Jafari M, Singh R, Muñoz J, Macian F, Cuervo AM. Juste YR, et al. Among authors: diaz a. Nat Cell Biol. 2021 Dec;23(12):1255-1270. doi: 10.1038/s41556-021-00800-z. Epub 2021 Dec 7. Nat Cell Biol. 2021. PMID: 34876687 Free PMC article.
Lysosomal mTORC2/PHLPP1/Akt Regulate Chaperone-Mediated Autophagy.
Arias E, Koga H, Diaz A, Mocholi E, Patel B, Cuervo AM. Arias E, et al. Among authors: diaz a. Mol Cell. 2015 Jul 16;59(2):270-84. doi: 10.1016/j.molcel.2015.05.030. Epub 2015 Jun 25. Mol Cell. 2015. PMID: 26118642 Free PMC article.
Humanin is an endogenous activator of chaperone-mediated autophagy.
Gong Z, Tasset I, Diaz A, Anguiano J, Tas E, Cui L, Kuliawat R, Liu H, Kühn B, Cuervo AM, Muzumdar R. Gong Z, et al. Among authors: diaz a. J Cell Biol. 2018 Feb 5;217(2):635-647. doi: 10.1083/jcb.201606095. Epub 2017 Nov 29. J Cell Biol. 2018. PMID: 29187525 Free PMC article.
Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome.
Bourdenx M, Martín-Segura A, Scrivo A, Rodriguez-Navarro JA, Kaushik S, Tasset I, Diaz A, Storm NJ, Xin Q, Juste YR, Stevenson E, Luengo E, Clement CC, Choi SJ, Krogan NJ, Mosharov EV, Santambrogio L, Grueninger F, Collin L, Swaney DL, Sulzer D, Gavathiotis E, Cuervo AM. Bourdenx M, et al. Among authors: diaz a. Cell. 2021 May 13;184(10):2696-2714.e25. doi: 10.1016/j.cell.2021.03.048. Epub 2021 Apr 22. Cell. 2021. PMID: 33891876 Free PMC article.
Proteome-wide analysis of chaperone-mediated autophagy targeting motifs.
Kirchner P, Bourdenx M, Madrigal-Matute J, Tiano S, Diaz A, Bartholdy BA, Will B, Cuervo AM. Kirchner P, et al. Among authors: diaz a. PLoS Biol. 2019 May 31;17(5):e3000301. doi: 10.1371/journal.pbio.3000301. eCollection 2019 May. PLoS Biol. 2019. PMID: 31150375 Free PMC article.
Protective role of chaperone-mediated autophagy against atherosclerosis.
Madrigal-Matute J, de Bruijn J, van Kuijk K, Riascos-Bernal DF, Diaz A, Tasset I, Martín-Segura A, Gijbels MJJ, Sander B, Kaushik S, Biessen EAL, Tiano S, Bourdenx M, Krause GJ, McCracken I, Baker AH, Jin H, Sibinga NES, Bravo-Cordero JJ, Macian F, Singh R, Rensen PCN, Berbée JFP, Pasterkamp G, Sluimer JC, Cuervo AM. Madrigal-Matute J, et al. Among authors: diaz a. Proc Natl Acad Sci U S A. 2022 Apr 5;119(14):e2121133119. doi: 10.1073/pnas.2121133119. Epub 2022 Apr 1. Proc Natl Acad Sci U S A. 2022. PMID: 35363568 Free PMC article.
Reduced endosomal microautophagy activity in aging associates with enhanced exocyst-mediated protein secretion.
Krause GJ, Diaz A, Jafari M, Khawaja RR, Agullo-Pascual E, Santiago-Fernández O, Richards AL, Chen KH, Dmitriev P, Sun Y, See SK, Abdelmohsen K, Mazan-Mamczarz K, Krogan NJ, Gorospe M, Swaney DL, Sidoli S, Bravo-Cordero JJ, Kampmann M, Cuervo AM. Krause GJ, et al. Among authors: diaz a. Aging Cell. 2022 Oct;21(10):e13713. doi: 10.1111/acel.13713. Epub 2022 Sep 18. Aging Cell. 2022. PMID: 36116133 Free PMC article.
Molecular determinants of the crosstalk between endosomal microautophagy and chaperone-mediated autophagy.
Krause GJ, Kirchner P, Stiller B, Morozova K, Diaz A, Chen KH, Krogan NJ, Agullo-Pascual E, Clement CC, Lindenau K, Swaney DL, Dilipkumar S, Bravo-Cordero JJ, Santambrogio L, Cuervo AM. Krause GJ, et al. Among authors: diaz a. Cell Rep. 2023 Dec 26;42(12):113529. doi: 10.1016/j.celrep.2023.113529. Epub 2023 Dec 6. Cell Rep. 2023. PMID: 38060380 Free PMC article.
3,102 results