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Rapid Bladder Interleukin-10 Synthesis in Response to Uropathogenic Escherichia coli Is Part of a Defense Strategy Triggered by the Major Bacterial Flagellar Filament FliC and Contingent on TLR5.
Acharya D, Sullivan MJ, Duell BL, Goh KGK, Katupitiya L, Gosling D, Chamoun MN, Kakkanat A, Chattopadhyay D, Crowley M, Crossman DK, Schembri MA, Ulett GC. Acharya D, et al. mSphere. 2019 Nov 27;4(6):e00545-19. doi: 10.1128/mSphere.00545-19. mSphere. 2019. PMID: 31776239 Free PMC article.
Restriction of chronic Escherichia coli urinary tract infection depends upon T cell-derived interleukin-17, a deficiency of which predisposes to flagella-driven bacterial persistence.
Chamoun MN, Sullivan MJ, Goh KGK, Acharya D, Ipe DS, Katupitiya L, Gosling D, Peters KM, Sweet MJ, Sester DP, Schembri MA, Ulett GC. Chamoun MN, et al. Among authors: acharya d. FASEB J. 2020 Nov;34(11):14572-14587. doi: 10.1096/fj.202000760R. Epub 2020 Sep 9. FASEB J. 2020. PMID: 32901999
Streptococcus agalactiae glyceraldehyde-3-phosphate dehydrogenase (GAPDH) elicits multiple cytokines from human cells and has a minor effect on bacterial persistence in the murine female reproductive tract.
Sullivan MJ, Goh KGK, Thapa R, Chattopadhyay D, Ipe DS, Duell BL, Katupitiya L, Gosling D, Acharya D, Ulett GC. Sullivan MJ, et al. Among authors: acharya d. Virulence. 2021 Dec;12(1):3015-3027. doi: 10.1080/21505594.2021.1989252. Virulence. 2021. PMID: 34643172 Free PMC article.
A SARS-CoV-2 targeted siRNA-nanoparticle therapy for COVID-19.
Idris A, Davis A, Supramaniam A, Acharya D, Kelly G, Tayyar Y, West N, Zhang P, McMillan CLD, Soemardy C, Ray R, O'Meally D, Scott TA, McMillan NAJ, Morris KV. Idris A, et al. Among authors: acharya d. Mol Ther. 2021 Jul 7;29(7):2219-2226. doi: 10.1016/j.ymthe.2021.05.004. Epub 2021 May 14. Mol Ther. 2021. PMID: 33992805 Free PMC article.
401 results