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Druglike, 18F-labeled PET Tracers Targeting Fibroblast Activation Protein.
Tanc M, Filippi N, Van Rymenant Y, Grintsevich S, Pintelon I, Verschuuren M, De Loose J, Verhulst E, Moon ES, Cianni L, Stroobants S, Augustyns K, Roesch F, De Meester I, Elvas F, Van der Veken P. Tanc M, et al. Among authors: de meester i. J Med Chem. 2024 May 9;67(9):7068-7087. doi: 10.1021/acs.jmedchem.3c02402. Epub 2024 Apr 24. J Med Chem. 2024. PMID: 38656144
Fluoro-olefins as peptidomimetic inhibitors of dipeptidyl peptidases.
Van der Veken P, Senten K, Kertèsz I, De Meester I, Lambeir AM, Maes MB, Scharpé S, Haemers A, Augustyns K. Van der Veken P, et al. Among authors: de meester i. J Med Chem. 2005 Mar 24;48(6):1768-80. doi: 10.1021/jm0495982. J Med Chem. 2005. PMID: 15771423
Acylated Gly-(2-cyano)pyrrolidines as inhibitors of fibroblast activation protein (FAP) and the issue of FAP/prolyl oligopeptidase (PREP)-selectivity.
Ryabtsova O, Jansen K, Van Goethem S, Joossens J, Cheng JD, Lambeir AM, De Meester I, Augustyns K, Van der Veken P. Ryabtsova O, et al. Among authors: de meester i. Bioorg Med Chem Lett. 2012 May 15;22(10):3412-7. doi: 10.1016/j.bmcl.2012.03.107. Epub 2012 Apr 4. Bioorg Med Chem Lett. 2012. PMID: 22525314
P2-substituted N-acylprolylpyrrolidine inhibitors of prolyl oligopeptidase: biochemical evaluation, binding mode determination, and assessment in a cellular model of synucleinopathy.
Van der Veken P, Fülöp V, Rea D, Gerard M, Van Elzen R, Joossens J, Cheng JD, Baekelandt V, De Meester I, Lambeir AM, Augustyns K. Van der Veken P, et al. Among authors: de meester i. J Med Chem. 2012 Nov 26;55(22):9856-67. doi: 10.1021/jm301060g. Epub 2012 Nov 13. J Med Chem. 2012. PMID: 23121075
Novel Small Molecule-Derived, Highly Selective Substrates for Fibroblast Activation Protein (FAP).
De Decker A, Vliegen G, Van Rompaey D, Peeraer A, Bracke A, Verckist L, Jansen K, Geiss-Friedlander R, Augustyns K, De Winter H, De Meester I, Lambeir AM, Van der Veken P. De Decker A, et al. Among authors: de winter h, de meester i. ACS Med Chem Lett. 2019 Jul 9;10(8):1173-1179. doi: 10.1021/acsmedchemlett.9b00191. eCollection 2019 Aug 8. ACS Med Chem Lett. 2019. PMID: 31413802 Free PMC article.
196 results