Mesrouze Y - Search Results

1

mRNA Display Identifies Potent, Paralog-Selective Peptidic Ligands for ARID1B.

Cremosnik GS, Mesrouze Y, Zueger P, Furkert D, Grandjean F, Argoti D, Mermet-Meillon F, Bauer MR, Brittain S, Rogemoser P, Yang W, Giovannoni J, McGregor L, Tang J, Knapp M, Holzinger S, Buhr S, Muller L, Leder L, Xie L, Fernandez C, Nieto-Oberhuber C, Chène P, Galli GG, Sesterhenn F. Cremosnik GS, et al. Among authors: mesrouze y. ACS Chem Biol. 2024 May 17;19(5):1142-1150. doi: 10.1021/acschembio.4c00083. Epub 2024 Apr 24. ACS Chem Biol. 2024. PMID: 38655884 Free PMC article.

2

Direct and selective pharmacological disruption of the YAP-TEAD interface by IAG933 inhibits Hippo-dependent and RAS-MAPK-altered cancers.

Chapeau EA, Sansregret L, Galli GG, Chène P, Wartmann M, Mourikis TP, Jaaks P, Baltschukat S, Barbosa IAM, Bauer D, Brachmann SM, Delaunay C, Estadieu C, Faris JE, Furet P, Harlfinger S, Hueber A, Jiménez Núñez E, Kodack DP, Mandon E, Martin T, Mesrouze Y, Romanet V, Scheufler C, Sellner H, Stamm C, Sterker D, Tordella L, Hofmann F, Soldermann N, Schmelzle T. Chapeau EA, et al. Among authors: mesrouze y. Nat Cancer. 2024 Apr 2. doi: 10.1038/s43018-024-00754-9. Online ahead of print. Nat Cancer. 2024. PMID: 38565920

3

Biochemical and Structural Characterization of a Peptidic Inhibitor of the YAP:TEAD Interaction That Binds to the α-Helix Pocket on TEAD.

Mesrouze Y, Gubler H, Villard F, Boesch R, Ottl J, Kallen J, Reid PC, Scheufler C, Marzinzik AL, Chène P. Mesrouze Y, et al. ACS Chem Biol. 2023 Mar 17;18(3):643-651. doi: 10.1021/acschembio.2c00936. Epub 2023 Feb 24. ACS Chem Biol. 2023. PMID: 36825662

4

N-terminal β-strand in YAP is critical for stronger binding to scalloped relative to TEAD transcription factor.

Bokhovchuk F, Mesrouze Y, Meyerhofer M, Fontana P, Zimmermann C, Villard F, Erdmann D, Kallen J, Scheufler C, Velez-Vega C, Chène P. Bokhovchuk F, et al. Among authors: mesrouze y. Protein Sci. 2023 Jan;32(1):e4545. doi: 10.1002/pro.4545. Protein Sci. 2023. PMID: 36522189 Free PMC article.

5

The First Class of Small Molecules Potently Disrupting the YAP-TEAD Interaction by Direct Competition.

Furet P, Bordas V, Le Douget M, Salem B, Mesrouze Y, Imbach-Weese P, Sellner H, Voegtle M, Soldermann N, Chapeau E, Wartmann M, Scheufler C, Fernandez C, Kallen J, Guagnano V, Chène P, Schmelzle T. Furet P, et al. Among authors: mesrouze y. ChemMedChem. 2022 Oct 6;17(19):e202200303. doi: 10.1002/cmdc.202200303. Epub 2022 Sep 2. ChemMedChem. 2022. PMID: 35950546

6

The role of lysine palmitoylation/myristoylation in the function of the TEAD transcription factors.

Mesrouze Y, Aguilar G, Meyerhofer M, Bokhovchuk F, Zimmermann C, Fontana P, Vissières A, Voshol H, Erdmann D, Affolter M, Chène P. Mesrouze Y, et al. Sci Rep. 2022 Mar 23;12(1):4984. doi: 10.1038/s41598-022-09127-7. Sci Rep. 2022. PMID: 35322151 Free PMC article.

7

Biochemical properties of VGLL4 from Homo sapiens and Tgi from Drosophila melanogaster and possible biological implications.

Mesrouze Y, Meyerhofer M, Zimmermann C, Fontana P, Erdmann D, Chène P. Mesrouze Y, et al. Protein Sci. 2021 Sep;30(9):1871-1881. doi: 10.1002/pro.4138. Epub 2021 Jun 8. Protein Sci. 2021. PMID: 34075638 Free PMC article.

8

Study of the TEAD-binding domain of the YAP protein from animal species.

Mesrouze Y, Bokhovchuk F, Meyerhofer M, Zimmermann C, Fontana P, Erdmann D, Chène P. Mesrouze Y, et al. Protein Sci. 2021 Feb;30(2):339-349. doi: 10.1002/pro.3988. Epub 2020 Nov 20. Protein Sci. 2021. PMID: 33146905 Free PMC article.

9

A new perspective on the interaction between the Vg/VGLL1-3 proteins and the TEAD transcription factors.

Mesrouze Y, Aguilar G, Bokhovchuk F, Martin T, Delaunay C, Villard F, Meyerhofer M, Zimmermann C, Fontana P, Wille R, Vorherr T, Erdmann D, Furet P, Scheufler C, Schmelzle T, Affolter M, Chène P. Mesrouze Y, et al. Sci Rep. 2020 Oct 15;10(1):17442. doi: 10.1038/s41598-020-74584-x. Sci Rep. 2020. PMID: 33060790 Free PMC article.

10

An Early Association between the α-Helix of the TEAD Binding Domain of YAP and TEAD Drives the Formation of the YAP:TEAD Complex.

Bokhovchuk F, Mesrouze Y, Meyerhofer M, Zimmermann C, Fontana P, Erdmann D, Jemth P, Chène P. Bokhovchuk F, et al. Among authors: mesrouze y. Biochemistry. 2020 May 19;59(19):1804-1812. doi: 10.1021/acs.biochem.0c00217. Epub 2020 Apr 30. Biochemistry. 2020. PMID: 32329346

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