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Antisense oligonucleotides targeting the miR-29b binding site in the GRN mRNA increase progranulin translation.
Aggarwal G, Banerjee S, Jones SA, Benchaar Y, Bélanger J, Sévigny M, Smith DM, Niehoff ML, Pavlack M, de Vera IMS, Petkau TL, Leavitt BR, Ling K, Jafar-Nejad P, Rigo F, Morley JE, Farr SA, Dutchak PA, Sephton CF, Nguyen AD. Aggarwal G, et al. Among authors: de vera ims. J Biol Chem. 2023 Dec;299(12):105475. doi: 10.1016/j.jbc.2023.105475. Epub 2023 Nov 18. J Biol Chem. 2023. PMID: 37981208 Free PMC article.
International Union of Basic and Clinical Pharmacology CXIII: Nuclear Receptor Superfamily-Update 2023.
Burris TP, de Vera IMS, Cote I, Flaveny CA, Wanninayake US, Chatterjee A, Walker JK, Steinauer N, Zhang J, Coons LA, Korach KS, Cain DW, Hollenberg AN, Webb P, Forrest D, Jetten AM, Edwards DP, Grimm SL, Hartig S, Lange CA, Richer JK, Sartorius CA, Tetel M, Billon C, Elgendy B, Hegazy L, Griffett K, Peinetti N, Burnstein KL, Hughes TS, Sitaula S, Stayrook KR, Culver A, Murray MH, Finck BN, Cidlowski JA. Burris TP, et al. Among authors: de vera ims. Pharmacol Rev. 2023 Nov;75(6):1233-1318. doi: 10.1124/pharmrev.121.000436. Epub 2023 Aug 16. Pharmacol Rev. 2023. PMID: 37586884 Free PMC article. Review.
Development and pharmacological evaluation of a new chemical series of potent pan-ERR agonists, identification of SLU-PP-915.
Hampton CS, Sitaula S, Billon C, Haynes K, Avdagic A, Wanninayake U, Adeyemi CM, Chatterjee A, Griffett K, Banerjee S, Burris SL, Schoepke E, Boehm T, Bess A, de Vera IMS, Burris TP, Walker JK. Hampton CS, et al. Among authors: de vera ims. Eur J Med Chem. 2023 Oct 5;258:115582. doi: 10.1016/j.ejmech.2023.115582. Epub 2023 Jun 25. Eur J Med Chem. 2023. PMID: 37421886
Identification of potent small molecule inhibitors of SARS-CoV-2 entry.
Mediouni S, Mou H, Otsuka Y, Jablonski JA, Adcock RS, Batra L, Chung DH, Rood C, de Vera IMS, Rahaim R Jr, Ullah S, Yu X, Getmanenko YA, Kennedy NM, Wang C, Nguyen TT, Hull M, Chen E, Bannister TD, Baillargeon P, Scampavia L, Farzan M, Valente ST, Spicer TP. Mediouni S, et al. Among authors: de vera ims. SLAS Discov. 2022 Jan;27(1):8-19. doi: 10.1016/j.slasd.2021.10.012. Epub 2021 Oct 23. SLAS Discov. 2022. PMID: 35058179 Free PMC article.
The Orphan Nuclear Receptor TLX Is a Receptor for Synthetic and Natural Retinoids.
Griffett K, Bedia-Diaz G, Hegazy L, de Vera IMS, Wanninayake US, Billon C, Koelblen T, Wilhelm ML, Burris TP. Griffett K, et al. Among authors: de vera ims. Cell Chem Biol. 2020 Oct 15;27(10):1272-1284.e4. doi: 10.1016/j.chembiol.2020.07.013. Epub 2020 Aug 6. Cell Chem Biol. 2020. PMID: 32763139 Free article.
Plasma cell-free DNA predicts pediatric cerebral malaria severity.
Vera IM, Kessler A, Ting LM, Harawa V, Keller T, Allen D, Njie M, Moss M, Soko M, Ahmadu A, Kadwala I, Ray S, Nyirenda TS, Mandala WL, Taylor TE, Rogerson SJ, Seydel KB, Kim K. Vera IM, et al. JCI Insight. 2020 Jun 18;5(12):e136279. doi: 10.1172/jci.insight.136279. JCI Insight. 2020. PMID: 32554925 Free PMC article.
41 results