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Sedentary behavior in mice induces metabolic inflexibility by suppressing skeletal muscle pyruvate metabolism.
Siripoksup P, Cao G, Cluntun AA, Maschek JA, Pearce Q, Lang MJ, Jeong MY, Eshima H, Ferrara PJ, Opurum PC, Mahmassani ZS, Peterlin AD, Watanabe S, Walsh MA, Taylor EB, Cox JE, Drummond MJ, Rutter J, Funai K. Siripoksup P, et al. Among authors: taylor eb. J Clin Invest. 2024 Apr 23:e167371. doi: 10.1172/JCI167371. Online ahead of print. J Clin Invest. 2024. PMID: 38652544 Free article.
Hepatic Mitochondrial Pyruvate Carrier 1 Is Required for Efficient Regulation of Gluconeogenesis and Whole-Body Glucose Homeostasis.
Gray LR, Sultana MR, Rauckhorst AJ, Oonthonpan L, Tompkins SC, Sharma A, Fu X, Miao R, Pewa AD, Brown KS, Lane EE, Dohlman A, Zepeda-Orozco D, Xie J, Rutter J, Norris AW, Cox JE, Burgess SC, Potthoff MJ, Taylor EB. Gray LR, et al. Among authors: taylor eb. Cell Metab. 2015 Oct 6;22(4):669-81. doi: 10.1016/j.cmet.2015.07.027. Epub 2015 Sep 3. Cell Metab. 2015. PMID: 26344103 Free PMC article.
Impaired skeletal muscle mitochondrial pyruvate uptake rewires glucose metabolism to drive whole-body leanness.
Sharma A, Oonthonpan L, Sheldon RD, Rauckhorst AJ, Zhu Z, Tompkins SC, Cho K, Grzesik WJ, Gray LR, Scerbo DA, Pewa AD, Cushing EM, Dyle MC, Cox JE, Adams C, Davies BS, Shields RK, Norris AW, Patti G, Zingman LV, Taylor EB. Sharma A, et al. Among authors: taylor eb. Elife. 2019 Jul 18;8:e45873. doi: 10.7554/eLife.45873. Elife. 2019. PMID: 31305240 Free PMC article.
Mitochondrial pyruvate carriers are required for myocardial stress adaptation.
Zhang Y, Taufalele PV, Cochran JD, Robillard-Frayne I, Marx JM, Soto J, Rauckhorst AJ, Tayyari F, Pewa AD, Gray LR, Teesch LM, Puchalska P, Funari TR, McGlauflin R, Zimmerman K, Kutschke WJ, Cassier T, Hitchcock S, Lin K, Kato KM, Stueve JL, Haff L, Weiss RM, Cox JE, Rutter J, Taylor EB, Crawford PA, Lewandowski ED, Des Rosiers C, Abel ED. Zhang Y, et al. Among authors: taylor eb. Nat Metab. 2020 Nov;2(11):1248-1264. doi: 10.1038/s42255-020-00288-1. Epub 2020 Oct 26. Nat Metab. 2020. PMID: 33106689 Free PMC article.
A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans.
Bricker DK, Taylor EB, Schell JC, Orsak T, Boutron A, Chen YC, Cox JE, Cardon CM, Van Vranken JG, Dephoure N, Redin C, Boudina S, Gygi SP, Brivet M, Thummel CS, Rutter J. Bricker DK, et al. Among authors: taylor eb. Science. 2012 Jul 6;337(6090):96-100. doi: 10.1126/science.1218099. Epub 2012 May 24. Science. 2012. PMID: 22628558 Free PMC article.
Publisher Correction: Mitochondrial pyruvate carriers are required for myocardial stress adaptation.
Zhang Y, Taufalele PV, Cochran JD, Robillard-Frayne I, Marx JM, Soto J, Rauckhorst AJ, Tayyari F, Pewa AD, Gray LR, Teesch LM, Puchalska P, Funari TR, McGlauflin R, Zimmerman K, Kutschke WJ, Cassier T, Hitchcock S, Lin K, Kato KM, Stueve JL, Haff L, Weiss RM, Cox JE, Rutter J, Taylor EB, Crawford PA, Lewandowski ED, Des Rosiers C, Abel ED. Zhang Y, et al. Among authors: taylor eb. Nat Metab. 2020 Dec;2(12):1498. doi: 10.1038/s42255-020-00322-2. Nat Metab. 2020. PMID: 33208925 No abstract available.
Identification of a protein mediating respiratory supercomplex stability.
Chen YC, Taylor EB, Dephoure N, Heo JM, Tonhato A, Papandreou I, Nath N, Denko NC, Gygi SP, Rutter J. Chen YC, et al. Among authors: taylor eb. Cell Metab. 2012 Mar 7;15(3):348-60. doi: 10.1016/j.cmet.2012.02.006. Cell Metab. 2012. PMID: 22405070 Free PMC article.
186 results