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In vivo alkaline comet assay: Statistical considerations on historical negative and positive control data.
Tug T, Duda JC, Menssen M, Bruce SW, Bringezu F, Dammann M, Frötschl R, Harm V, Ickstadt K, Igl BW, Jarzombek M, Kellner R, Lott J, Pfuhler S, Plappert-Helbig U, Rahnenführer J, Schulz M, Vaas L, Vasquez M, Ziegler V, Ziemann C. Tug T, et al. Among authors: pfuhler s. Regul Toxicol Pharmacol. 2024 Mar;148:105583. doi: 10.1016/j.yrtph.2024.105583. Epub 2024 Feb 22. Regul Toxicol Pharmacol. 2024. PMID: 38401761 Free article.
Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT).
Parsons BL, Beal MA, Dearfield KL, Douglas GR, Gi M, Gollapudi BB, Heflich RH, Horibata K, Kenyon M, Long AS, Lovell DP, Lynch AM, Myers MB, Pfuhler S, Vespa A, Zeller A, Johnson GE, White PA. Parsons BL, et al. Among authors: pfuhler s. Environ Mol Mutagen. 2024 Jun 3. doi: 10.1002/em.22599. Online ahead of print. Environ Mol Mutagen. 2024. PMID: 38828778 Review.
Interlaboratory validation of the ToxTracker assay: An in vitro reporter assay for mechanistic genotoxicity assessment.
Hendriks G, Adriaens E, Allemang A, Clements J, Cole G, Derr R, Engel M, Hamel A, Kidd D, Kellum S, Kiyota T, Myhre A, Naëssens V, Pfuhler S, Roy M, Settivari R, Schuler M, Zeller A, van Benthem J, Vanparys P, Kirkland D. Hendriks G, et al. Among authors: pfuhler s. Environ Mol Mutagen. 2024 Jan-Feb;65(1-2):4-24. doi: 10.1002/em.22592. Epub 2024 Mar 28. Environ Mol Mutagen. 2024. PMID: 38545858
Interpretation of in vitro concentration-response data for risk assessment and regulatory decision-making: Report from the 2022 IWGT quantitative analysis expert working group meeting.
Beal MA, Chen G, Dearfield KL, Gi M, Gollapudi B, Heflich RH, Horibata K, Long AS, Lovell DP, Parsons BL, Pfuhler S, Wills J, Zeller A, Johnson G, White PA. Beal MA, et al. Among authors: pfuhler s. Environ Mol Mutagen. 2023 Dec 19. doi: 10.1002/em.22582. Online ahead of print. Environ Mol Mutagen. 2023. PMID: 38115239 Review.
Measuring DNA modifications with the comet assay: a compendium of protocols.
Collins A, Møller P, Gajski G, Vodenková S, Abdulwahed A, Anderson D, Bankoglu EE, Bonassi S, Boutet-Robinet E, Brunborg G, Chao C, Cooke MS, Costa C, Costa S, Dhawan A, de Lapuente J, Bo' CD, Dubus J, Dusinska M, Duthie SJ, Yamani NE, Engelward B, Gaivão I, Giovannelli L, Godschalk R, Guilherme S, Gutzkow KB, Habas K, Hernández A, Herrero O, Isidori M, Jha AN, Knasmüller S, Kooter IM, Koppen G, Kruszewski M, Ladeira C, Laffon B, Larramendy M, Hégarat LL, Lewies A, Lewinska A, Liwszyc GE, de Cerain AL, Manjanatha M, Marcos R, Milić M, de Andrade VM, Moretti M, Muruzabal D, Novak M, Oliveira R, Olsen AK, Owiti N, Pacheco M, Pandey AK, Pfuhler S, Pourrut B, Reisinger K, Rojas E, Rundén-Pran E, Sanz-Serrano J, Shaposhnikov S, Sipinen V, Smeets K, Stopper H, Teixeira JP, Valdiglesias V, Valverde M, van Acker F, van Schooten FJ, Vasquez M, Wentzel JF, Wnuk M, Wouters A, Žegura B, Zikmund T, Langie SAS, Azqueta A. Collins A, et al. Among authors: pfuhler s. Nat Protoc. 2023 Mar;18(3):929-989. doi: 10.1038/s41596-022-00754-y. Epub 2023 Jan 27. Nat Protoc. 2023. PMID: 36707722 Free PMC article. Review.
Quantitative in vitro to in vivo extrapolation of genotoxicity data provides protective estimates of in vivo dose.
Beal MA, Audebert M, Barton-Maclaren T, Battaion H, Bemis JC, Cao X, Chen C, Dertinger SD, Froetschl R, Guo X, Johnson G, Hendriks G, Khoury L, Long AS, Pfuhler S, Settivari RS, Wickramasuriya S, White P. Beal MA, et al. Among authors: pfuhler s. Environ Mol Mutagen. 2023 Feb;64(2):105-122. doi: 10.1002/em.22521. Epub 2022 Dec 22. Environ Mol Mutagen. 2023. PMID: 36495195
76 results