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A 4-gene prognostic index for enhancing acute myeloid leukaemia survival prediction.
Ortiz Rojas CA, Pereira-Martins DA, Bellido More CC, Sternadt D, Weinhäuser I, Hilberink JR, Coelho-Silva JL, Thomé CH, Ferreira GA, Ammatuna E, Huls G, Valk PJ, Schuringa JJ, Rego EM. Ortiz Rojas CA, et al. Among authors: thome ch. Br J Haematol. 2024 Apr 23. doi: 10.1111/bjh.19472. Online ahead of print. Br J Haematol. 2024. PMID: 38651345
NTAL is associated with treatment outcome, cell proliferation and differentiation in acute promyelocytic leukemia.
Thomé CH, Ferreira GA, Pereira-Martins DA, Dos Santos GA, Ortiz CA, de Souza LEB, Sobral LM, Silva CLA, Scheucher PS, Gil CD, Leopoldino AM, Silveira DRA, Coelho-Silva JL, Traina F, Koury LC, Melo RAM, Bittencourt R, Pagnano K, Pasquini R, Nunes EC, Fagundes EM, Gloria ABF, Kerbauy FR, Chauffaille ML, Keating A, Tallman MS, Ribeiro RC, Dillon R, Ganser A, Löwenberg B, Valk P, Lo-Coco F, Sanz MA, Berliner N, Faça VM, Rego EM. Thomé CH, et al. Sci Rep. 2020 Jun 25;10(1):10315. doi: 10.1038/s41598-020-66223-2. Sci Rep. 2020. PMID: 32587277 Free PMC article.
ΔNp73 overexpression promotes resistance to apoptosis but does not cooperate with PML/RARA in the induction of an APL-leukemic phenotype.
Lucena-Araujo AR, Coelho-Silva JL, Pereira-Martins DA, Thomé C, Scheucher PS, Lange AP, Paiva HH, Hemmelgarn BT, Morais-Sobral MC, Azevedo EA, Franca-Neto PL, Franca RF, Silva CL, Krause A, Rego EM. Lucena-Araujo AR, et al. Oncotarget. 2017 Jan 31;8(5):8475-8483. doi: 10.18632/oncotarget.14295. Oncotarget. 2017. PMID: 28035072 Free PMC article.
High ΔNp73/TAp73 ratio is associated with poor prognosis in acute promyelocytic leukemia.
Lucena-Araujo AR, Kim HT, Thomé C, Jacomo RH, Melo RA, Bittencourt R, Pasquini R, Pagnano K, Glória AB, Chauffaille Mde L, Athayde M, Chiattone CS, Mito I, Bendlin R, Souza C, Bortolheiro C, Coelho-Silva JL, Schrier SL, Tallman MS, Grimwade D, Ganser A, Berliner N, Ribeiro RC, Lo-Coco F, Löwenberg B, Sanz MA, Rego EM. Lucena-Araujo AR, et al. Blood. 2015 Nov 12;126(20):2302-6. doi: 10.1182/blood-2015-01-623330. Epub 2015 Oct 1. Blood. 2015. PMID: 26429976 Free PMC article. Clinical Trial.
The lipid raft protein NTAL participates in AKT signaling in mantle cell lymphoma.
Ferreira GA, Thomé CH, Simão AMS, Scheucher PS, Silva CLA, Chahud F, Ciancaglini P, Leopoldino AM, Rego EM, Faça VM, Dos Santos GA. Ferreira GA, et al. Among authors: thome ch. Leuk Lymphoma. 2019 Nov;60(11):2658-2668. doi: 10.1080/10428194.2019.1607326. Epub 2019 May 7. Leuk Lymphoma. 2019. PMID: 31060403
Sequesterpene Lactones Isolated from a Brazilian Cerrado Plant (Eremanthus spp.) as Anti-Proliferative Compounds, Characterized by Functional and Proteomic Analysis, are Candidates for New Therapeutics in Glioblastoma.
Izumi C, Laure HJ, Barbosa NG, Thomé CH, Ferreira GA, Sousa JPB, Lopes NP, Rosa JC. Izumi C, et al. Among authors: thome ch. Int J Mol Sci. 2020 Jul 1;21(13):4713. doi: 10.3390/ijms21134713. Int J Mol Sci. 2020. PMID: 32630308 Free PMC article.
32 results