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Page 1
Abatacept increases T cell exhaustion in early RA individuals who carry HLA risk alleles.
Long SA, Muir VS, Jones BE, Wall VZ, Ylescupidez A, Hocking AM, Pribitzer S, Thorpe J, Fuchs B, Wiedeman AE, Tatum M, Lambert K, Uchtenhagen H, Speake C, Ng B, Heubeck AT, Torgerson TR, Savage AK, Maldonado MA, Ray N, Khaychuk V, Liu J, Linsley PS, Buckner JH. Long SA, et al. Among authors: wiedeman ae. Front Immunol. 2024 Apr 8;15:1383110. doi: 10.3389/fimmu.2024.1383110. eCollection 2024. Front Immunol. 2024. PMID: 38650930 Free PMC article.
A simple strategy for sample annotation error detection in cytometry datasets.
Smithmyer ME, Wiedeman AE, Skibinski DAG, Savage AK, Acosta-Vega C, Scheiding S, Gersuk VH, O'Rourke C, Long SA, Buckner JH, Speake C. Smithmyer ME, et al. Among authors: wiedeman ae. Cytometry A. 2022 Apr;101(4):351-360. doi: 10.1002/cyto.a.24525. Epub 2021 Dec 29. Cytometry A. 2022. PMID: 34967113 Free article.
Deep immune phenotyping reveals similarities between aging, Down syndrome, and autoimmunity.
Lambert K, Moo KG, Arnett A, Goel G, Hu A, Flynn KJ, Speake C, Wiedeman AE, Gersuk VH, Linsley PS, Greenbaum CJ, Long SA, Partridge R, Buckner JH, Khor B. Lambert K, et al. Among authors: wiedeman ae. Sci Transl Med. 2022 Jan 12;14(627):eabi4888. doi: 10.1126/scitranslmed.abi4888. Epub 2022 Jan 12. Sci Transl Med. 2022. PMID: 35020411 Free PMC article.
Guidelines for standardizing T-cell cytometry assays to link biomarkers, mechanisms, and disease outcomes in type 1 diabetes.
Yang JHM, Ward-Hartstonge KA, Perry DJ, Blanchfield JL, Posgai AL, Wiedeman AE, Diggins K, Rahman A, Tree TIM, Brusko TM, Levings MK, James EA, Kent SC, Speake C, Homann D, Long SA; Immunology of Diabetes Society T-Cell Cytometry Group. Yang JHM, et al. Among authors: wiedeman ae. Eur J Immunol. 2022 Mar;52(3):372-388. doi: 10.1002/eji.202049067. Epub 2022 Jan 28. Eur J Immunol. 2022. PMID: 35025103 Free PMC article.
A first-in-human, open-label Phase 1b and a randomised, double-blind Phase 2a clinical trial in recent-onset type 1 diabetes with AG019 as monotherapy and in combination with teplizumab.
Mathieu C, Wiedeman A, Cerosaletti K, Long SA, Serti E, Cooney L, Vermeiren J, Caluwaerts S, Van Huynegem K, Steidler L, Blomme S, Rottiers P, Nepom GT, Herold KC; AG019-T1D-101 Trial Investigators. Mathieu C, et al. Diabetologia. 2024 Jan;67(1):27-41. doi: 10.1007/s00125-023-06014-2. Epub 2023 Oct 2. Diabetologia. 2024. PMID: 37782353 Free PMC article. Clinical Trial.
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