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Intra-bone bone marrow transplantation from hCD47 transgenic pigs to baboons prolongs chimerism to >60 days and promotes increased porcine lung transplant survival.
Watanabe H, Ariyoshi Y, Pomposelli T, Takeuchi K, Ekanayake-Alper DK, Boyd LK, Arn SJ, Sahara H, Shimizu A, Ayares D, Lorber MI, Sykes M, Sachs DH, Yamada K. Watanabe H, et al. Among authors: yamada k. Xenotransplantation. 2020 Jan;27(1):e12552. doi: 10.1111/xen.12552. Epub 2019 Sep 23. Xenotransplantation. 2020. PMID: 31544995 Free PMC article.
Consistent survival in consecutive cases of life-supporting porcine kidney xenotransplantation using 10GE source pigs.
Eisenson D, Hisadome Y, Santillan M, Iwase H, Chen W, Shimizu A, Schulick A, Gu D, Akbar A, Zhou A, Koenig K, Kuravi K, Rahman F, Sorrells L, Burdorf L, DeSmet K, Warren D, Peterson L, Lorber M, Ayares D, Cameron A, Yamada K. Eisenson D, et al. Among authors: yamada k. Nat Commun. 2024 Apr 18;15(1):3361. doi: 10.1038/s41467-024-47679-6. Nat Commun. 2024. PMID: 38637524 Free PMC article.
Expression of human CD47 in pig glomeruli prevents proteinuria and prolongs graft survival following pig-to-baboon xenotransplantation.
Takeuchi K, Ariyoshi Y, Shimizu A, Okumura Y, Cara-Fuentes G, Garcia GE, Pomposelli T, Watanabe H, Boyd L, Ekanayake-Alper DK, Amarnath D, Sykes M, Sachs DH, Johnson RJ, Yamada K. Takeuchi K, et al. Among authors: yamada k. Xenotransplantation. 2021 Nov;28(6):e12708. doi: 10.1111/xen.12708. Epub 2021 Aug 21. Xenotransplantation. 2021. PMID: 34418164 Free PMC article.
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