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Sex-dependent differences in tissue and blood n-3 PUFA levels following ALA or ALA + DHA feeding of liver-specific Elovl2-KO and control mice.
Prostaglandins Leukot Essent Fatty Acids. 2024 May 14;201:102621. doi: 10.1016/j.plefa.2024.102621. Online ahead of print.
Prostaglandins Leukot Essent Fatty Acids. 2024.
PMID: 38763083
Free article.
Dietary docosahexaenoic acid (DHA) downregulates liver DHA synthesis by inhibiting eicosapentaenoic acid elongation.
Metherel AH, Valenzuela R, Klievik BJ, Cisbani G, Rotarescu RD, Gonzalez-Soto M, Cruciani-Guglielmacci C, Layé S, Magnan C, Mutch DM, Bazinet RP.
Metherel AH, et al. Among authors: klievik bj.
J Lipid Res. 2024 Apr 20;65(6):100548. doi: 10.1016/j.jlr.2024.100548. Online ahead of print.
J Lipid Res. 2024.
PMID: 38649096
Free PMC article.
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Blood and tissue docosahexaenoic acid (DHA, 22:6n-3) turnover rates from Ahiflower® oil are not different than from DHA ethyl ester oil in a diet switch mouse model.
Metherel AH, Klievik BJ, Cisbani G, Smith ME, Cumberford G, Bazinet RP.
Metherel AH, et al. Among authors: klievik bj.
Biochim Biophys Acta Mol Cell Biol Lipids. 2024 Jan;1869(1):159422. doi: 10.1016/j.bbalip.2023.159422. Epub 2023 Nov 17.
Biochim Biophys Acta Mol Cell Biol Lipids. 2024.
PMID: 37977491
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Protein concentrations and activities of fatty acid desaturase and elongase enzymes in liver, brain, testicle, and kidney from mice: Substrate dependency.
Valenzuela R, Metherel AH, Cisbani G, Smith ME, Chouinard-Watkins R, Klievik BJ, Videla LA, Bazinet RP.
Valenzuela R, et al. Among authors: klievik bj.
Biofactors. 2024 Jan-Feb;50(1):89-100. doi: 10.1002/biof.1992. Epub 2023 Jul 20.
Biofactors. 2024.
PMID: 37470206
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Measuring brain docosahexaenoic acid turnover as a marker of metabolic consumption.
Klievik BJ, Tyrrell AD, Chen CT, Bazinet RP.
Klievik BJ, et al.
Pharmacol Ther. 2023 Aug;248:108437. doi: 10.1016/j.pharmthera.2023.108437. Epub 2023 May 17.
Pharmacol Ther. 2023.
PMID: 37201738
Review.
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Novel 13C enrichment technique reveals early turnover of DHA in peripheral tissues.
Klievik BJ, Metherel AH, Cisbani G, Valenzuela R, Bazinet RP.
Klievik BJ, et al.
J Lipid Res. 2023 May;64(5):100357. doi: 10.1016/j.jlr.2023.100357. Epub 2023 Mar 21.
J Lipid Res. 2023.
PMID: 36948271
Free PMC article.
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