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Endothelial IGF-1 receptor mediates crosstalk with the gut wall to regulate microbiota in obesity.
Haywood NJ, Luk C, Bridge KI, Drozd M, Makava N, Skromna A, Maccannell A, Ozber CH, Warmke N, Wilkinson CG, Watt NT, Koch-Paszkowski J, Teh I, Boyle JH, Smart S, Schneider JE, Yuldasheva NY, Roberts LD, Beech DJ, Sukumar P, Wheatcroft SB, Cubbon RM, Kearney MT. Haywood NJ, et al. Among authors: wheatcroft sb. EMBO Rep. 2021 May 5;22(5):e50767. doi: 10.15252/embr.202050767. Epub 2021 May 2. EMBO Rep. 2021. PMID: 33934497 Free PMC article.
Nox2 NADPH oxidase has a critical role in insulin resistance-related endothelial cell dysfunction.
Sukumar P, Viswambharan H, Imrie H, Cubbon RM, Yuldasheva N, Gage M, Galloway S, Skromna A, Kandavelu P, Santos CX, Gatenby VK, Smith J, Beech DJ, Wheatcroft SB, Channon KM, Shah AM, Kearney MT. Sukumar P, et al. Among authors: wheatcroft sb. Diabetes. 2013 Jun;62(6):2130-4. doi: 10.2337/db12-1294. Epub 2013 Jan 24. Diabetes. 2013. PMID: 23349484 Free PMC article.
Haploinsufficiency of the insulin-like growth factor-1 receptor enhances endothelial repair and favorably modifies angiogenic progenitor cell phenotype.
Yuldasheva NY, Rashid ST, Haywood NJ, Cordell P, Mughal R, Viswambharan H, Imrie H, Sukumar P, Cubbon RM, Aziz A, Gage M, Mbonye KA, Smith J, Galloway S, Skromna A, Scott DJ, Kearney MT, Wheatcroft SB. Yuldasheva NY, et al. Among authors: wheatcroft sb. Arterioscler Thromb Vasc Biol. 2014 Sep;34(9):2051-8. doi: 10.1161/ATVBAHA.114.304121. Epub 2014 Jul 10. Arterioscler Thromb Vasc Biol. 2014. PMID: 25012136
Endothelial SHIP2 Suppresses Nox2 NADPH Oxidase-Dependent Vascular Oxidative Stress, Endothelial Dysfunction, and Systemic Insulin Resistance.
Watt NT, Gage MC, Patel PA, Viswambharan H, Sukumar P, Galloway S, Yuldasheva NY, Imrie H, Walker AMN, Griffin KJ, Makava N, Skromna A, Bridge K, Beech DJ, Schurmans S, Wheatcroft SB, Kearney MT, Cubbon RM. Watt NT, et al. Among authors: wheatcroft sb. Diabetes. 2017 Nov;66(11):2808-2821. doi: 10.2337/db17-0062. Epub 2017 Aug 22. Diabetes. 2017. PMID: 28830894 Free article.
143 results