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Rationale and design of the PACIFIC-PRESERVED (PhenomApping, ClassIFication and Innovation for Cardiac dysfunction in patients with heart failure and PRESERVED left ventricular ejection fraction) study.
Hulot JS, Janiak P, Boutinaud P, Boutouyrie P, Chézalviel-Guilbert F, Christophe JJ, Cohen A, Damy T, Djadi-Prat J, Firat H, Hervé PY, Isnard R, Jondeau G, Mousseaux E, Pernot M, Prot P, Tyl B, Soulat G, Logeart D; PACIFIC consortium. Hulot JS, et al. Among authors: janiak p. Arch Cardiovasc Dis. 2024 May;117(5):332-342. doi: 10.1016/j.acvd.2024.02.011. Epub 2024 Apr 12. Arch Cardiovasc Dis. 2024. PMID: 38644067 Free article.
SAR340835, a Novel Selective Na+/Ca2+ Exchanger Inhibitor, Improves Cardiac Function and Restores Sympathovagal Balance in Heart Failure.
Pelat M, Barbe F, Daveu C, Ly-Nguyen L, Lartigue T, Marque S, Tavares G, Ballet V, Guillon JM, Steinmeyer K, Wirth K, Gögelein H, Arndt P, Rackelmann N, Weston J, Bellevergue P, McCort G, Trellu M, Lucats L, Beauverger P, Pruniaux-Harnist MP, Janiak P, Chézalviel-Guilbert F. Pelat M, et al. Among authors: janiak p. J Pharmacol Exp Ther. 2021 May;377(2):293-304. doi: 10.1124/jpet.120.000238. Epub 2021 Feb 18. J Pharmacol Exp Ther. 2021. PMID: 33602875
Reversion of cardiac dysfunction by a novel orally available calcium/calmodulin-dependent protein kinase II inhibitor, RA306, in a genetic model of dilated cardiomyopathy.
Beauverger P, Ozoux ML, Bégis G, Glénat V, Briand V, Philippo MC, Daveu C, Tavares G, Roy S, Corbier A, Briand P, Dorchies O, Bauchet AL, Nicolai E, Duclos O, Tamarelle D, Pruniaux MP, Muslin AJ, Janiak P. Beauverger P, et al. Among authors: janiak p. Cardiovasc Res. 2020 Feb 1;116(2):329-338. doi: 10.1093/cvr/cvz097. Cardiovasc Res. 2020. PMID: 31038167
The oral Ca/calmodulin-dependent kinase II inhibitor RA608 improves contractile function and prevents arrhythmias in heart failure.
Mustroph J, Drzymalski M, Baier M, Pabel S, Biedermann A, Memmel B, Durczok M, Neef S, Sag CM, Floerchinger B, Rupprecht L, Schmid C, Zausig Y, Bégis G, Briand V, Ozoux ML, Tamarelle D, Ballet V, Janiak P, Beauverger P, Maier LS, Wagner S. Mustroph J, et al. Among authors: janiak p. ESC Heart Fail. 2020 Oct;7(5):2871-2883. doi: 10.1002/ehf2.12895. Epub 2020 Jul 20. ESC Heart Fail. 2020. PMID: 32691522 Free PMC article.
High Glucose Activates YAP Signaling to Promote Vascular Inflammation.
Ortillon J, Le Bail JC, Villard E, Léger B, Poirier B, Girardot C, Beeske S, Ledein L, Blanchard V, Brieu P, Naimi S, Janiak P, Guillot E, Meloni M. Ortillon J, et al. Among authors: janiak p. Front Physiol. 2021 Jun 4;12:665994. doi: 10.3389/fphys.2021.665994. eCollection 2021. Front Physiol. 2021. PMID: 34149446 Free PMC article.
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