Buettner R - Search Results

1

8-Cl-Ado and 8-NH₂-Ado synergize with venetoclax to target the methionine-MAT2A-SAM axis in acute myeloid leukemia.

Guo J, Buettner R, Du L, Li Z, Liu W, Su R, Chen Z, Che Y, Zhang Y, Ma R, Nguyen LXT, Moore RE, Khyatiben P, Chen MH, Patrick P, Wu X, Marcucci G, Wang L, Horne D, Chen J, Yang Y, Rosen ST. Guo J, et al. Among authors: buettner r. Leukemia. 2024 Apr 20. doi: 10.1038/s41375-024-02222-w. Online ahead of print. Leukemia. 2024. PMID: 38643304

2

8-chloro-adenosine activity in FLT3-ITD acute myeloid leukemia.

Buettner R, Nguyen LXT, Kumar B, Morales C, Liu C, Chen LS, Pemovska T, Synold TW, Palmer J, Thompson R, Li L, Hoang DH, Zhang B, Ghoda L, Kowolik C, Kontro M, Leitch C, Wennerberg K, Yu X, Chen CC, Horne D, Gandhi V, Pullarkat V, Marcucci G, Rosen ST. Buettner R, et al. J Cell Physiol. 2019 Sep;234(9):16295-16303. doi: 10.1002/jcp.28294. Epub 2019 Feb 15. J Cell Physiol. 2019. PMID: 30770553 Free PMC article.

3

Targeting the metabolic vulnerability of acute myeloid leukemia blasts with a combination of venetoclax and 8-chloro-adenosine.

Buettner R, Nguyen LXT, Morales C, Chen MH, Wu X, Chen LS, Hoang DH, Hernandez Vargas S, Pullarkat V, Gandhi V, Marcucci G, Rosen ST. Buettner R, et al. J Hematol Oncol. 2021 Apr 26;14(1):70. doi: 10.1186/s13045-021-01076-4. J Hematol Oncol. 2021. PMID: 33902674 Free PMC article.

4

Synergy of Venetoclax and 8-Chloro-Adenosine in AML: The Interplay of rRNA Inhibition and Fatty Acid Metabolism.

Hoang DH, Morales C, Rodriguez IR, Valerio M, Guo J, Chen MH, Wu X, Horne D, Gandhi V, Chen LS, Zhang B, Pullarkat V, Rosen ST, Marcucci G, Buettner R, Nguyen LXT. Hoang DH, et al. Among authors: buettner r. Cancers (Basel). 2022 Mar 11;14(6):1446. doi: 10.3390/cancers14061446. Cancers (Basel). 2022. PMID: 35326597 Free PMC article.

5

Arsenic Trioxide and Venetoclax Synergize against AML Progenitors by ROS Induction and Inhibition of Nrf2 Activation.

Hoang DH, Buettner R, Valerio M, Ghoda L, Zhang B, Kuo YH, Rosen ST, Burnett J, Marcucci G, Pullarkat V, Nguyen LXT. Hoang DH, et al. Among authors: buettner r. Int J Mol Sci. 2022 Jun 12;23(12):6568. doi: 10.3390/ijms23126568. Int J Mol Sci. 2022. PMID: 35743010 Free PMC article.

6

Targeting the methionine-methionine adenosyl transferase 2A- S -adenosyl methionine axis for cancer therapy.

Guo J, Yang Y, Buettner R, Rosen ST. Guo J, et al. Among authors: buettner r. Curr Opin Oncol. 2022 Sep 1;34(5):546-551. doi: 10.1097/CCO.0000000000000870. Epub 2022 Jul 5. Curr Opin Oncol. 2022. PMID: 35788128 Free PMC article. Review.

7

OST-01, a natural product from Baccharis coridifolia, targets c-Myc-dependent ribogenesis in acute myeloid leukemia.

Kang H, Hoang DH, Valerio M, Pathak K, Zhang L, Buettner R, Chen F, Estrella K, Graff W, Li Z, Xie J, Horne D, Kuo YH, Zhang B, Pirrotte P, Nguyen LXT, Marcucci G. Kang H, et al. Among authors: buettner r. Leukemia. 2024 Mar;38(3):657-662. doi: 10.1038/s41375-024-02146-5. Epub 2024 Jan 17. Leukemia. 2024. PMID: 38233463 Free PMC article. No abstract available.

8

Glucocorticoid receptor expression in multiple myeloma patients is a predictor of survival.

Pozhitkov A, Rosenzweig M, Pichiorri F, Gunes EG, Buettner R, Keats JJ, Rosen ST. Pozhitkov A, et al. Among authors: buettner r. Leuk Lymphoma. 2020 Dec;61(14):3493-3497. doi: 10.1080/10428194.2020.1811860. Epub 2020 Sep 13. Leuk Lymphoma. 2020. PMID: 32921213 Free PMC article.

9

A phase 1 trial of 8-chloro-adenosine in relapsed/refractory acute myeloid leukemia: An evaluation of safety and pharmacokinetics.

Pullarkat V, Chen LS, Palmer J, Zhang J, Synold TW, Buettner R, Truong Nguyen LX, Marcucci G, Tsai NC, Wang Y, O'Hearn J, Gandhi V, Rosen ST. Pullarkat V, et al. Among authors: buettner r. Cancer. 2024 Mar 1;130(5):727-739. doi: 10.1002/cncr.35077. Epub 2023 Oct 28. Cancer. 2024. PMID: 37897709 Clinical Trial.

10

Repurposing leflunomide for relapsed/refractory multiple myeloma: a phase 1 study.

Rosenzweig M, Palmer J, Tsai NC, Synold T, Wu X, Tao S, Hammond SN, Buettner R, Duarte L, Htut M, Karanes C, Nathwani N, Pichiorri F, Sahebi F, Sanchez JF, Chowdhury A, Krishnan A, Forman SJ, Rosen ST. Rosenzweig M, et al. Among authors: buettner r. Leuk Lymphoma. 2020 Jul;61(7):1669-1677. doi: 10.1080/10428194.2020.1742900. Epub 2020 Apr 8. Leuk Lymphoma. 2020. PMID: 32268821 Free PMC article. Clinical Trial.

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