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Discovery of 4-(1,2,4-Oxadiazol-5-yl)azepan-2-one Derivatives as a New Class of Cannabinoid Type 2 Receptor Agonists for the Treatment of Inflammatory Pain.
Nan J, Liu J, Lin G, Zhang S, Xia A, Zhou P, Zhou Y, Zhang J, Zhao J, Zhang S, Huang C, Wang Y, Hu Q, Chen J, Xiang M, Yang X, Yang S. Nan J, et al. Among authors: zhou y, zhou p. J Med Chem. 2023 Mar 9;66(5):3460-3483. doi: 10.1021/acs.jmedchem.2c01943. Epub 2023 Feb 23. J Med Chem. 2023. PMID: 36821347
Cryo-EM structures of human GPR34 enable the identification of selective antagonists.
Xia A, Yong X, Zhang C, Lin G, Jia G, Zhao C, Wang X, Hao Y, Wang Y, Zhou P, Yang X, Deng Y, Wu C, Chen Y, Zhu J, Tang X, Liu J, Zhang S, Zhang J, Xu Z, Hu Q, Zhao J, Yue Y, Yan W, Su Z, Wei Y, Zhou R, Dong H, Shao Z, Yang S. Xia A, et al. Among authors: zhou p, zhou r. Proc Natl Acad Sci U S A. 2023 Sep 26;120(39):e2308435120. doi: 10.1073/pnas.2308435120. Epub 2023 Sep 21. Proc Natl Acad Sci U S A. 2023. PMID: 37733739 Free PMC article.
Interleukin-37 promotes colitis-associated carcinogenesis via SIGIRR-mediated cytotoxic T cells dysfunction.
Wang Z, Zeng FL, Hu YW, Wang XY, Zhao FL, Zhou P, Hu J, Xiao YY, Hu ZL, Guo MF, Wei XQ, Liu X, Huang NY, Zhang J, Chen SW, Cheng J, Zheng HP, Zhou H, Zhao QX, Zhang C, Hao Y, Zou S, Gui YY, Yu JD, Gu LN, Yue CC, Zhang HZ, Wu WL, Zhou YF, Zhou XK, Shen GB, Teng X, Li J. Wang Z, et al. Among authors: zhou h, zhou p, zhou yf, zhou xk. Signal Transduct Target Ther. 2022 Jan 20;7(1):19. doi: 10.1038/s41392-021-00820-z. Signal Transduct Target Ther. 2022. PMID: 35046386 Free PMC article.
Intestinal dysbiosis exacerbates the pathogenesis of psoriasis-like phenotype through changes in fatty acid metabolism.
Zhao Q, Yu J, Zhou H, Wang X, Zhang C, Hu J, Hu Y, Zheng H, Zeng F, Yue C, Gu L, Wang Z, Zhao F, Zhou P, Zhang H, Huang N, Wu W, Zhou Y, Li J. Zhao Q, et al. Among authors: zhou h, zhou y, zhou p. Signal Transduct Target Ther. 2023 Jan 30;8(1):40. doi: 10.1038/s41392-022-01219-0. Signal Transduct Target Ther. 2023. PMID: 36710269 Free PMC article.
8,876 results