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Long-term hepatitis B virus infection of rhesus macaques requires suppression of host immunity.
Biswas S, Rust LN, Wettengel JM, Yusova S, Fischer M, Carson JN, Johnson J, Wei L, Thode T, Kaadige MR, Sharma S, Agbaria M, Bimber BN, Tu T, Protzer U, Ploss A, Smedley JV, Golomb G, Sacha JB, Burwitz BJ. Biswas S, et al. Among authors: wettengel jm. Nat Commun. 2022 May 30;13(1):2995. doi: 10.1038/s41467-022-30593-0. Nat Commun. 2022. PMID: 35637225 Free PMC article.
Hepatitis B Virus Targets Lipid Transport Pathways to Infect Hepatocytes.
Esser K, Cheng X, Wettengel JM, Lucifora J, Hansen-Palmus L, Austen K, Roca Suarez AA, Heintz S, Testoni B, Nebioglu F, Pham MT, Yang S, Zernecke A, Wohlleber D, Ringelhan M, Broxtermann M, Hartmann D, Hüser N, Mergner J, Pichlmair A, Thasler WE, Heikenwalder M, Gasteiger G, Blutke A, Walch A, Knolle PA, Bartenschlager R, Protzer U. Esser K, et al. Among authors: wettengel jm. Cell Mol Gastroenterol Hepatol. 2023;16(2):201-221. doi: 10.1016/j.jcmgh.2023.03.011. Epub 2023 Apr 11. Cell Mol Gastroenterol Hepatol. 2023. PMID: 37054914 Free PMC article.
Interferon-induced degradation of the persistent hepatitis B virus cccDNA form depends on ISG20.
Stadler D, Kächele M, Jones AN, Hess J, Urban C, Schneider J, Xia Y, Oswald A, Nebioglu F, Bester R, Lasitschka F, Ringelhan M, Ko C, Chou WM, Geerlof A, van de Klundert MA, Wettengel JM, Schirmacher P, Heikenwälder M, Schreiner S, Bartenschlager R, Pichlmair A, Sattler M, Unger K, Protzer U. Stadler D, et al. Among authors: wettengel jm. EMBO Rep. 2021 Jun 4;22(6):e49568. doi: 10.15252/embr.201949568. Epub 2021 May 9. EMBO Rep. 2021. PMID: 33969602 Free PMC article.
Interferon-γ and Tumor Necrosis Factor-α Produced by T Cells Reduce the HBV Persistence Form, cccDNA, Without Cytolysis.
Xia Y, Stadler D, Lucifora J, Reisinger F, Webb D, Hösel M, Michler T, Wisskirchen K, Cheng X, Zhang K, Chou WM, Wettengel JM, Malo A, Bohne F, Hoffmann D, Eyer F, Thimme R, Falk CS, Thasler WE, Heikenwalder M, Protzer U. Xia Y, et al. Among authors: wettengel jm. Gastroenterology. 2016 Jan;150(1):194-205. doi: 10.1053/j.gastro.2015.09.026. Epub 2015 Sep 28. Gastroenterology. 2016. PMID: 26416327 Free article.
Vector-Mediated Delivery of Human Major Histocompatibility Complex-I into Hepatocytes Enables Investigation of T Cell Receptor-Redirected Hepatitis B Virus-Specific T Cells in Mice, and in Macaque Cell Cultures.
Festag J, Festag MM, Asen T, Wettengel JM, Mück-Häusl MA, Abdulhaqq S, Stahl-Hennig C, Sacha JB, Burwitz BJ, Protzer U, Wisskirchen K. Festag J, et al. Among authors: wettengel jm. Hum Gene Ther. 2023 Dec;34(23-24):1204-1218. doi: 10.1089/hum.2023.035. Epub 2023 Dec 5. Hum Gene Ther. 2023. PMID: 37747811
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