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Liver-targeted polymeric prodrugs delivered subcutaneously improve tafenoquine therapeutic window for malaria radical cure.
Pottenger AE, Roy D, Srinivasan S, Chavas TEJ, Vlaskin V, Ho DK, Livingston VC, Maktabi M, Lin H, Zhang J, Pybus B, Kudyba K, Roth A, Senter P, Tyson G, Huber HE, Wesche D, Rochford R, Burke PA, Stayton PS. Pottenger AE, et al. Among authors: stayton ps. Sci Adv. 2024 Apr 19;10(16):eadk4492. doi: 10.1126/sciadv.adk4492. Epub 2024 Apr 19. Sci Adv. 2024. PMID: 38640243 Free PMC article.
Liver-targeted polymeric prodrugs of 8-aminoquinolines for malaria radical cure.
Srinivasan S, Roy D, Chavas TEJ, Vlaskin V, Ho DK, Pottenger A, LeGuyader CLM, Maktabi M, Strauch P, Jackson C, Flaherty SM, Lin H, Zhang J, Pybus B, Li Q, Huber HE, Burke PA, Wesche D, Rochford R, Stayton PS. Srinivasan S, et al. Among authors: stayton ps. J Control Release. 2021 Mar 10;331:213-227. doi: 10.1016/j.jconrel.2020.12.046. Epub 2020 Dec 27. J Control Release. 2021. PMID: 33378692
Arming Immune Cell Therapeutics with Polymeric Prodrugs.
López CL, Brempelis KJ, Matthaei JF, Montgomery KS, Srinivasan S, Roy D, Huang F, Kreuser SA, Gardell JL, Blumenthal I, Chiefari J, Jensen MC, Crane CA, Stayton PS. López CL, et al. Among authors: stayton ps. Adv Healthc Mater. 2022 May;11(9):e2101944. doi: 10.1002/adhm.202101944. Epub 2021 Dec 17. Adv Healthc Mater. 2022. PMID: 34889072 Free PMC article.
A nanofiber based antiviral (TAF) prodrug delivery system.
Dart A, Roy D, Vlaskin V, Limqueco E, Lowe NM, Srinivasan S, Ratner DM, Bhave M, Stayton P, Kingshott P. Dart A, et al. Biomater Adv. 2022 Feb;133:112626. doi: 10.1016/j.msec.2021.112626. Epub 2022 Jan 4. Biomater Adv. 2022. PMID: 35039198
Macromolecular Cargo Encapsulation via In Vitro Assembly of Two-Component Protein Nanoparticles.
Herpoldt KL, López CL, Sappington I, Pham MN, Srinivasan S, Netland J, Montgomery KS, Roy D, Prossnitz AN, Ellis D, Wargacki AJ, Pepper M, Convertine AJ, Stayton PS, King NP. Herpoldt KL, et al. Among authors: stayton ps. Adv Healthc Mater. 2024 Apr;13(11):e2303910. doi: 10.1002/adhm.202303910. Epub 2024 Feb 11. Adv Healthc Mater. 2024. PMID: 38180445
207 results