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Reversible Chemical Modification of Antibody Effector Function Mitigates Unwanted Systemic Immune Activation.
Moquist PN, Zhang X, Leiske CI, Eng-Duncan NM, Zeng W, Bindman NA, Wo SW, Wong A, Henderson CM, Crowder K, Lyon R, Doronina SO, Senter PD, Neff-LaFord HD, Sussman D, Gardai SJ, Levengood MR. Moquist PN, et al. Among authors: senter pd. Bioconjug Chem. 2024 May 24. doi: 10.1021/acs.bioconjchem.4c00212. Online ahead of print. Bioconjug Chem. 2024. PMID: 38789102
Liver-targeted polymeric prodrugs delivered subcutaneously improve tafenoquine therapeutic window for malaria radical cure.
Pottenger AE, Roy D, Srinivasan S, Chavas TEJ, Vlaskin V, Ho DK, Livingston VC, Maktabi M, Lin H, Zhang J, Pybus B, Kudyba K, Roth A, Senter P, Tyson G, Huber HE, Wesche D, Rochford R, Burke PA, Stayton PS. Pottenger AE, et al. Among authors: senter p. Sci Adv. 2024 Apr 19;10(16):eadk4492. doi: 10.1126/sciadv.adk4492. Epub 2024 Apr 19. Sci Adv. 2024. PMID: 38640243 Free PMC article.
Antibody-drug conjugates come of age in oncology.
Dumontet C, Reichert JM, Senter PD, Lambert JM, Beck A. Dumontet C, et al. Among authors: senter pd. Nat Rev Drug Discov. 2023 Aug;22(8):641-661. doi: 10.1038/s41573-023-00709-2. Epub 2023 Jun 12. Nat Rev Drug Discov. 2023. PMID: 37308581 Review.
Precision cancer targeting with antibody pairs.
Lawrence RT, Senter PD. Lawrence RT, et al. Among authors: senter pd. Nat Biotechnol. 2022 Oct;40(10):1434-1435. doi: 10.1038/s41587-022-01401-3. Nat Biotechnol. 2022. PMID: 35879363 No abstract available.
Development of Novel Antibody-Camptothecin Conjugates.
Lyski RD, Bou LB, Lau UY, Meyer DW, Cochran JH, Okeley NM, Emmerton KK, Zapata F, Simmons JK, Trueblood ES, Ortiz DJ, Zaval MC, Snead KM, Jin S, Farr LM, Ryan MC, Senter PD, Jeffrey SC. Lyski RD, et al. Among authors: senter pd. Mol Cancer Ther. 2021 Feb;20(2):329-339. doi: 10.1158/1535-7163.MCT-20-0526. Epub 2020 Dec 3. Mol Cancer Ther. 2021. PMID: 33273058
Structure-activity relationships of tubulysin analogues.
Courter JR, Hamilton JZ, Hendrick NR, Zaval M, Waight AB, Lyon RP, Senter PD, Jeffrey SC, Burke PJ. Courter JR, et al. Among authors: senter pd. Bioorg Med Chem Lett. 2020 Jul 15;30(14):127241. doi: 10.1016/j.bmcl.2020.127241. Epub 2020 May 5. Bioorg Med Chem Lett. 2020. PMID: 32527543
148 results