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Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages.
Mandula JK, Sierra-Mondragon RA, Jimenez RV, Chang D, Mohamed E, Chang S, Vazquez-Martinez JA, Cao Y, Anadon CM, Lee SB, Das S, Rocha-Munguba L, Pham VM, Li R, Tarhini AA, Furqan M, Dalton W, Churchman M, Moran-Segura CM, Nguyen J, Perez B, Kojetin DJ, Obermayer A, Yu X, Chen A, Shaw TI, Conejo-Garcia JR, Rodriguez PC. Mandula JK, et al. Among authors: rodriguez pc. Immunity. 2024 May 14;57(5):1124-1140.e9. doi: 10.1016/j.immuni.2024.03.020. Epub 2024 Apr 17. Immunity. 2024. PMID: 38636522
Neglected no more: B cell-mediated anti-tumor immunity.
Conejo-Garcia JR, Biswas S, Chaurio R, Rodriguez PC. Conejo-Garcia JR, et al. Among authors: rodriguez pc. Semin Immunol. 2023 Jan;65:101707. doi: 10.1016/j.smim.2022.101707. Epub 2022 Dec 15. Semin Immunol. 2023. PMID: 36527759 Free PMC article. Review.
PATH-SURVEYOR: pathway level survival enquiry for immuno-oncology and drug repurposing.
Obermayer AN, Chang D, Nobles G, Teng M, Tan AC, Wang X, Chen YA, Eschrich S, Rodriguez PC, Grass GD, Meshinchi S, Tarhini A, Chen DT, Shaw TI. Obermayer AN, et al. Among authors: rodriguez pc. BMC Bioinformatics. 2023 Jun 28;24(1):266. doi: 10.1186/s12859-023-05393-y. BMC Bioinformatics. 2023. PMID: 37380943 Free PMC article.
Targeting intracellular oncoproteins with dimeric IgA promotes expulsion from the cytoplasm and immune-mediated control of epithelial cancers.
Biswas S, Mandal G, Anadon CM, Chaurio RA, Lopez-Bailon LU, Nagy MZ, Mine JA, Hänggi K, Sprenger KB, Innamarato P, Harro CM, Powers JJ, Johnson J, Fang B, Eysha M, Nan X, Li R, Perez BA, Curiel TJ, Yu X, Rodriguez PC, Conejo-Garcia JR. Biswas S, et al. Among authors: rodriguez pc. Immunity. 2023 Nov 14;56(11):2570-2583.e6. doi: 10.1016/j.immuni.2023.09.013. Epub 2023 Oct 30. Immunity. 2023. PMID: 37909039 Free article.
Glucose-driven histone lactylation promotes the immunosuppressive activity of monocyte-derived macrophages in glioblastoma.
De Leo A, Ugolini A, Yu X, Scirocchi F, Scocozza D, Peixoto B, Pace A, D'Angelo L, Liu JKC, Etame AB, Rughetti A, Nuti M, Santoro A, Vogelbaum MA, Conejo-Garcia JR, Rodriguez PC, Veglia F. De Leo A, et al. Among authors: rodriguez pc. Immunity. 2024 May 14;57(5):1105-1123.e8. doi: 10.1016/j.immuni.2024.04.006. Epub 2024 May 3. Immunity. 2024. PMID: 38703775
A preclinical model of patient-derived cerebrospinal fluid circulating tumor cells for experimental therapeutics in leptomeningeal disease from melanoma.
Law V, Chen Z, Vena F, Smalley I, Macaulay R, Evernden BR, Tran N, Pina Y, Puskas J, Caceres G, Bayle S, Johnson J, Liu JKC, Etame A, Vogelbaum M, Rodriguez P, Duckett D, Czerniecki B, Chen A, Smalley KSM, Forsyth PA. Law V, et al. Neuro Oncol. 2022 Oct 3;24(10):1673-1686. doi: 10.1093/neuonc/noac054. Neuro Oncol. 2022. PMID: 35213727 Free PMC article.
Enniatin A inhibits the chaperone Hsp90 and unleashes the immune system against triple-negative breast cancer.
Eisa NH, Crowley VM, Elahi A, Kommalapati VK, Serwetnyk MA, Llbiyi T, Lu S, Kainth K, Jilani Y, Marasco D, El Andaloussi A, Lee S, Tsai FTF, Rodriguez PC, Munn D, Celis E, Korkaya H, Debbab A, Blagg B, Chadli A. Eisa NH, et al. Among authors: rodriguez pc. iScience. 2023 Oct 24;26(12):108308. doi: 10.1016/j.isci.2023.108308. eCollection 2023 Dec 15. iScience. 2023. PMID: 38025772 Free PMC article.
147 results