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JAK inhibition during the early phase of SARS-CoV-2 infection worsens kidney injury by suppressing endogenous antiviral activity in mice.
Sakai H, Kamuro H, Tokunoh N, Izawa T, Tamiya S, Yamamoto A, Tanaka S, Okuzaki D, Ono C, Matsuura Y, Okada Y, Yoshioka Y, Fujio Y, Obana M. Sakai H, et al. Among authors: obana m. Am J Physiol Renal Physiol. 2024 Jun 1;326(6):F931-F941. doi: 10.1152/ajprenal.00011.2024. Epub 2024 Apr 18. Am J Physiol Renal Physiol. 2024. PMID: 38634132 Free article.
Therapeutic administration of IL-11 exhibits the postconditioning effects against ischemia-reperfusion injury via STAT3 in the heart.
Obana M, Miyamoto K, Murasawa S, Iwakura T, Hayama A, Yamashita T, Shiragaki M, Kumagai S, Miyawaki A, Takewaki K, Matsumiya G, Maeda M, Yoshiyama M, Nakayama H, Fujio Y. Obana M, et al. Am J Physiol Heart Circ Physiol. 2012 Sep 1;303(5):H569-77. doi: 10.1152/ajpheart.00060.2012. Epub 2012 Jun 15. Am J Physiol Heart Circ Physiol. 2012. PMID: 22707562 Free article.
163 results