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Integrative common and rare variant analyses provide insights into the genetic architecture of liver cirrhosis.
Ghouse J, Sveinbjörnsson G, Vujkovic M, Seidelin AS, Gellert-Kristensen H, Ahlberg G, Tragante V, Rand SA, Brancale J, Vilarinho S, Lundegaard PR, Sørensen E, Erikstrup C, Bruun MT, Jensen BA, Brunak S, Banasik K, Ullum H; DBDS Genomic Consortium; Verweij N, Lotta L, Baras A; Regeneron Genetics Center; Mirshahi T, Carey DJ; Geisinger-Regeneron DiscovEHR Collaboration; VA Million Veteran Program; Kaplan DE, Lynch J, Morgan T, Schwantes-An TH, Dochtermann DR, Pyarajan S, Tsao PS; Estonian Biobank Research Team; Laisk T, Mägi R, Kozlitina J, Tybjærg-Hansen A, Jones D, Knowlton KU, Nadauld L, Ferkingstad E, Björnsson ES, Ulfarsson MO, Sturluson Á, Sulem P, Pedersen OB, Ostrowski SR, Gudbjartsson DF, Stefansson K, Olesen MS, Chang KM, Holm H, Bundgaard H, Stender S. Ghouse J, et al. Among authors: lundegaard pr. Nat Genet. 2024 May;56(5):827-837. doi: 10.1038/s41588-024-01720-y. Epub 2024 Apr 17. Nat Genet. 2024. PMID: 38632349 Free PMC article.
mc1r Pathway regulation of zebrafish melanosome dispersion.
Richardson J, Lundegaard PR, Reynolds NL, Dorin JR, Porteous DJ, Jackson IJ, Patton EE. Richardson J, et al. Among authors: lundegaard pr. Zebrafish. 2008 Dec;5(4):289-95. doi: 10.1089/zeb.2008.0541. Zebrafish. 2008. PMID: 19133827
A Multi-Site Assessment of Anesthetic Overdose, Hypothermic Shock, and Electrical Stunning as Methods of Euthanasia for Zebrafish (Danio rerio) Embryos and Larvae.
Mocho JP, Lang F, Valentin G, Bedu S, McKimm R, Ramos J, Saavedra Torres Y, Wheatley SE, Higgins J, Millington ME, Lundegaard PR, Chamorro Valverde R, Jenčič V, von Krogh K. Mocho JP, et al. Among authors: lundegaard pr. Biology (Basel). 2022 Apr 1;11(4):546. doi: 10.3390/biology11040546. Biology (Basel). 2022. PMID: 35453745 Free PMC article.
Small molecule screening identifies targetable zebrafish pigmentation pathways.
Colanesi S, Taylor KL, Temperley ND, Lundegaard PR, Liu D, North TE, Ishizaki H, Kelsh RN, Patton EE. Colanesi S, et al. Among authors: lundegaard pr. Pigment Cell Melanoma Res. 2012 Mar;25(2):131-43. doi: 10.1111/j.1755-148X.2012.00977.x. Pigment Cell Melanoma Res. 2012. PMID: 22252091
Rare truncating variants in the sarcomeric protein titin associate with familial and early-onset atrial fibrillation.
Ahlberg G, Refsgaard L, Lundegaard PR, Andreasen L, Ranthe MF, Linscheid N, Nielsen JB, Melbye M, Haunsø S, Sajadieh A, Camp L, Olesen SP, Rasmussen S, Lundby A, Ellinor PT, Holst AG, Svendsen JH, Olesen MS. Ahlberg G, et al. Among authors: lundegaard pr. Nat Commun. 2018 Oct 17;9(1):4316. doi: 10.1038/s41467-018-06618-y. Nat Commun. 2018. PMID: 30333491 Free PMC article.
Early sarcomere and metabolic defects in a zebrafish pitx2c cardiac arrhythmia model.
Collins MM, Ahlberg G, Hansen CV, Guenther S, Marín-Juez R, Sokol AM, El-Sammak H, Piesker J, Hellsten Y, Olesen MS, Stainier DYR, Lundegaard PR. Collins MM, et al. Among authors: lundegaard pr. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24115-24121. doi: 10.1073/pnas.1913905116. Epub 2019 Nov 8. Proc Natl Acad Sci U S A. 2019. PMID: 31704768 Free PMC article.
26 results