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Induced Regulatory T Cells as Immunotherapy in Allotransplantation and Autoimmunity: Challenges and Opportunities.
J Leukoc Biol. 2024 Apr 17:qiae062. doi: 10.1093/jleuko/qiae062. Online ahead of print.
J Leukoc Biol. 2024.
PMID: 38630873
Highly purified and functionally stable in vitro expanded allospecific Tr1 cells expressing immunosuppressive graft-homing receptors as new candidates for cell therapy in solid organ transplantation.
Arteaga-Cruz S, Cortés-Hernández A, Alvarez-Salazar EK, Rosas-Cortina K, Aguilera-Sandoval C, Morales-Buenrostro LE, Alberú-Gómez JM, Soldevila G.
Arteaga-Cruz S, et al.
Front Immunol. 2023 Feb 24;14:1062456. doi: 10.3389/fimmu.2023.1062456. eCollection 2023.
Front Immunol. 2023.
PMID: 36911743
Free PMC article.
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Highly Purified Alloantigen-Specific Tregs From Healthy and Chronic Kidney Disease Patients Can Be Long-Term Expanded, Maintaining a Suppressive Phenotype and Function in the Presence of Inflammatory Cytokines.
Cortés-Hernández A, Alvarez-Salazar EK, Arteaga-Cruz S, Rosas-Cortina K, Linares N, Alberú Gómez JM, Soldevila G.
Cortés-Hernández A, et al. Among authors: arteaga cruz s.
Front Immunol. 2021 Oct 28;12:686530. doi: 10.3389/fimmu.2021.686530. eCollection 2021.
Front Immunol. 2021.
PMID: 34777330
Free PMC article.
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Large-Scale Generation of Human Allospecific Induced Tregs With Functional Stability for Use in Immunotherapy in Transplantation.
Alvarez-Salazar EK, Cortés-Hernández A, Arteaga-Cruz S, Alberú-Gómez J, Soldevila G.
Alvarez-Salazar EK, et al. Among authors: arteaga cruz s.
Front Immunol. 2020 Apr 2;11:375. doi: 10.3389/fimmu.2020.00375. eCollection 2020.
Front Immunol. 2020.
PMID: 32300340
Free PMC article.
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Ex vivo expansion of regulatory T cells from long-term Belatacept-treated kidney transplant patients restores their phenotype and suppressive function but not their FOXP3 TSDR demethylation status.
Cortés-Hernández A, Alvarez-Salazar E, Arteaga-Cruz S, Alberu-Gómez J, Soldevila G.
Cortés-Hernández A, et al. Among authors: arteaga cruz s.
Cell Immunol. 2020 Feb;348:104044. doi: 10.1016/j.cellimm.2020.104044. Epub 2020 Jan 14.
Cell Immunol. 2020.
PMID: 32005344
Clinical Trial.
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