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Serum Matrix Metalloproteinase 7 Is a Diagnostic Biomarker of Biliary Injury and Fibrosis in Pediatric Autoimmune Liver Disease.
Lam S, Singh R, Dillman JR, Trout AT, Serai SD, Sharma D, Sheridan R, Su W, Fei L, Karns R, Haramija MM, Ridgway G, Goldfinger M, Squires JE, Denson LA, Hyams JS, Miethke AG. Lam S, et al. Among authors: karns r. Hepatol Commun. 2020 Sep 24;4(11):1680-1693. doi: 10.1002/hep4.1589. eCollection 2020 Nov. Hepatol Commun. 2020. PMID: 33163837 Free PMC article.
Pharmacological inhibition of apical sodium-dependent bile acid transporter changes bile composition and blocks progression of sclerosing cholangitis in multidrug resistance 2 knockout mice.
Miethke AG, Zhang W, Simmons J, Taylor AE, Shi T, Shanmukhappa SK, Karns R, White S, Jegga AG, Lages CS, Nkinin S, Keller BT, Setchell KD. Miethke AG, et al. Among authors: karns r. Hepatology. 2016 Feb;63(2):512-23. doi: 10.1002/hep.27973. Epub 2015 Aug 21. Hepatology. 2016. PMID: 26172874 Free PMC article.
PKM2-dependent metabolic skewing of hepatic Th17 cells regulates pathogenesis of non-alcoholic fatty liver disease.
Moreno-Fernandez ME, Giles DA, Oates JR, Chan CC, Damen MSMA, Doll JR, Stankiewicz TE, Chen X, Chetal K, Karns R, Weirauch MT, Romick-Rosendale L, Xanthakos SA, Sheridan R, Szabo S, Shah AS, Helmrath MA, Inge TH, Deshmukh H, Salomonis N, Divanovic S. Moreno-Fernandez ME, et al. Among authors: karns r. Cell Metab. 2021 Jun 1;33(6):1187-1204.e9. doi: 10.1016/j.cmet.2021.04.018. Epub 2021 May 17. Cell Metab. 2021. PMID: 34004162 Free PMC article.
FXR-Gankyrin axis is involved in development of pediatric liver cancer.
Valanejad L, Lewis K, Wright M, Jiang Y, D'Souza A, Karns R, Sheridan R, Gupta A, Bove K, Witte D, Geller J, Tiao G, Nelson DL, Timchenko L, Timchenko N. Valanejad L, et al. Among authors: karns r. Carcinogenesis. 2017 Jul 1;38(7):738-747. doi: 10.1093/carcin/bgx050. Carcinogenesis. 2017. PMID: 28535186 Free PMC article.
Peroxisomal β-oxidation regulates whole body metabolism, inflammatory vigor, and pathogenesis of nonalcoholic fatty liver disease.
Moreno-Fernandez ME, Giles DA, Stankiewicz TE, Sheridan R, Karns R, Cappelletti M, Lampe K, Mukherjee R, Sina C, Sallese A, Bridges JP, Hogan SP, Aronow BJ, Hoebe K, Divanovic S. Moreno-Fernandez ME, et al. Among authors: karns r. JCI Insight. 2018 Mar 22;3(6):e93626. doi: 10.1172/jci.insight.93626. JCI Insight. 2018. PMID: 29563328 Free PMC article.
96 results