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BiSim Tool: a binding simulation tool to aid and simplify ligand-binding assay design and development.
Bioanalysis. 2024 Apr 17. doi: 10.4155/bio-2023-0242. Online ahead of print.
Bioanalysis. 2024.
PMID: 38629337
A biomarker assay validation approach tailored to the context of use and bioanalytical platform.
Hickford ES, Dejager L, Yuill D, Kotian A, Shankar S, Staelens L, Ulrichts H, Lewis S, Louber J, Williams A, Le Provost GS, Cutler P.
Hickford ES, et al.
Bioanalysis. 2023 Jul;15(13):757-771. doi: 10.4155/bio-2023-0110. Epub 2023 Aug 1.
Bioanalysis. 2023.
PMID: 37526064
Review.
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Target occupancy biomarker assay development using a conformation-selective antibody against small-molecule-bound TNF.
Hickford ES, O'Connell J, Maloney A, Florian P, Johnston GI, Rospo CC, Herrmann M, Wright S, Bourne T.
Hickford ES, et al.
Bioanalysis. 2023 Mar;15(6):343-359. doi: 10.4155/bio-2022-0231. Epub 2023 Apr 7.
Bioanalysis. 2023.
PMID: 37026566
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A conformation-selective monoclonal antibody against a small molecule-stabilised signalling-deficient form of TNF.
Lightwood DJ, Munro RJ, Porter J, McMillan D, Carrington B, Turner A, Scott-Tucker A, Hickford ES, Schmidt A, Fox D 3rd, Maloney A, Ceska T, Bourne T, O'Connell J, Lawson ADG.
Lightwood DJ, et al. Among authors: hickford es.
Nat Commun. 2021 Jan 25;12(1):583. doi: 10.1038/s41467-020-20825-6.
Nat Commun. 2021.
PMID: 33495445
Free PMC article.
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