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B cells infected with Type 2 Epstein-Barr virus (EBV) have increased NFATc1/NFATc2 activity and enhanced lytic gene expression in comparison to Type 1 EBV infection.
Romero-Masters JC, Huebner SM, Ohashi M, Bristol JA, Benner BE, Barlow EA, Turk GL, Nelson SE, Baiu DC, Van Sciver N, Ranheim EA, Gumperz J, Sherer NM, Farrell PJ, Johannsen EC, Kenney SC. Romero-Masters JC, et al. Among authors: nelson se. PLoS Pathog. 2020 Feb 14;16(2):e1008365. doi: 10.1371/journal.ppat.1008365. eCollection 2020 Feb. PLoS Pathog. 2020. PMID: 32059024 Free PMC article.
EBNA2-deleted Epstein-Barr virus (EBV) isolate, P3HR1, causes Hodgkin-like lymphomas and diffuse large B cell lymphomas with type II and Wp-restricted latency types in humanized mice.
Li C, Romero-Masters JC, Huebner S, Ohashi M, Hayes M, Bristol JA, Nelson SE, Eichelberg MR, Van Sciver N, Ranheim EA, Scott RS, Johannsen EC, Kenney SC. Li C, et al. Among authors: nelson se. PLoS Pathog. 2020 Jun 15;16(6):e1008590. doi: 10.1371/journal.ppat.1008590. eCollection 2020 Jun. PLoS Pathog. 2020. PMID: 32542010 Free PMC article.
Reduced IRF4 expression promotes lytic phenotype in Type 2 EBV-infected B cells.
Bristol JA, Brand J, Ohashi M, Eichelberg MR, Casco A, Nelson SE, Hayes M, Romero-Masters JC, Baiu DC, Gumperz JE, Johannsen EC, Dinh HQ, Kenney SC. Bristol JA, et al. Among authors: nelson se. PLoS Pathog. 2022 Apr 26;18(4):e1010453. doi: 10.1371/journal.ppat.1010453. eCollection 2022 Apr. PLoS Pathog. 2022. PMID: 35472072 Free PMC article.
Type 1 and Type 2 Epstein-Barr viruses induce proliferation, and inhibit differentiation, in infected telomerase-immortalized normal oral keratinocytes.
Singh DR, Nelson SE, Pawelski AS, Cantres-Velez JA, Kansra AS, Pauly NP, Bristol JA, Hayes M, Ohashi M, Casco A, Lee D, Fogarty SA, Lambert PF, Johannsen EC, Kenney SC. Singh DR, et al. Among authors: nelson se. PLoS Pathog. 2022 Oct 3;18(10):e1010868. doi: 10.1371/journal.ppat.1010868. eCollection 2022 Oct. PLoS Pathog. 2022. PMID: 36190982 Free PMC article.
231 results