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Characterization of structural, biochemical, pharmacokinetic, and pharmacodynamic properties of the LSD1 inhibitor bomedemstat in preclinical models.
Jasmine S, Mandl A, Krueger TEG, Dalrymple SL, Antony L, Dias J, Celatka CA, Tapper AE, Kleppe M, Kanayama M, Jing Y, Speranzini V, Wang YZ, Luo J, Trock BJ, Denmeade SR, Carducci MA, Mattevi A, Rienhoff HY Jr, Isaacs JT, Nathaniel Brennen W. Jasmine S, et al. Among authors: dalrymple sl. Prostate. 2024 Apr 15. doi: 10.1002/pros.24707. Online ahead of print. Prostate. 2024. PMID: 38619005
Third generation quinoline-3-carboxamide transcriptional disrupter of HDAC4, HIF-1α, and MEF-2 signaling for metastatic castration-resistant prostate cancer.
Isaacs JT, Dalrymple SL, Antony L, Marc Rosen D, Coleman IM, Nelson PS, Kostova M, Murray IA, Perdew GH, Denmeade SR, Akinboye ES, Brennen WN. Isaacs JT, et al. Among authors: dalrymple sl. Prostate. 2023 Nov;83(15):1470-1493. doi: 10.1002/pros.24606. Epub 2023 Aug 9. Prostate. 2023. PMID: 37559436
Microparticle Encapsulation of a Prostate-targeted Biologic for the Treatment of Liver Metastases in a Preclinical Model of Castration-resistant Prostate Cancer.
Rogers OC, Antony L, Levy O, Joshi N, Simons BW, Dalrymple SL, Rosen DM, Pickering A, Lan H, Kuang H, Ranganath SH, Zheng L, Karp JM, Howard SP, Denmeade SR, Isaacs JT, Brennen WN. Rogers OC, et al. Among authors: dalrymple sl. Mol Cancer Ther. 2020 Nov;19(11):2353-2362. doi: 10.1158/1535-7163.MCT-20-0227. Epub 2020 Sep 17. Mol Cancer Ther. 2020. PMID: 32943549 Free PMC article.
24 results